557 results

Evaluation of platelet concentrate prescription in pediatric patients at a tertiary care hospital

Camila Augusta Victorino ORCID logo , João Carlos Pina Faria ORCID logo , Fabíola Isabel Suano-Souza ORCID logo , Roseli Oselka Saccardo Sarni ORCID logo

DOI: 10.31744/einstein_journal/2019AO4720

ABSTRACT Objective: To verify the adequacy of platelet concentrate prescription by pediatricians in different pediatric sectors of a general hospital. Methods: A cross-sectional study evaluating 218/227 platelet concentrate records in children and adolescents (zero to 13 years old), from January 2007 to April 2015, by the pediatricians of the emergency room, sick bay and intensive care unit. The requisitions were excluded in patients with hematological diseases and those without the number of platelets. Results: Children under 12 months received 98 […]

Sarcopenia and sarcopenic obesity as prognostic predictors in hospitalized elderly patients with acute myocardial infarction

Natália de Moraes Santana ORCID logo , Roberta Maria Lins Mendes ORCID logo , Nadja Fernandes da Silva ORCID logo , Cláudia Porto Sabino Pinho ORCID logo

DOI: 10.31744/einstein_journal/2019AO4632

ABSTRACT Objective: To investigate the potential value of sarcopenia and sarcopenic obesity as prognostic predictors in hospitalized elderly patients with acute myocardial infarction. Methods: A cross-sectional study based on data collected from elderly patients with acute myocardial infarction, admitted to a public hospital located in the Northeastern region of Brazil, from April to July 2015. The diagnosis of sarcopenia was based on muscle mass, muscle strength and physical performance measurements. Cardiovascular risk and prognostic markers, such as troponin and creatine […]

Dissatisfaction about body image and associated factors: a study of young undergraduate students

Laleska Pâmela Rodrigues da Silva ORCID logo , Ana Rita de Oliveira Tucan ORCID logo , Elisana Lima Rodrigues ORCID logo , Patrícia Vieira Del Ré ORCID logo , Priscila Milene Angelo Sanches ORCID logo , Deise Bresan ORCID logo

DOI: 10.31744/einstein_journal/2019AO4642

ABSTRACT Objective: To verify the prevalence of dissatisfaction with body image and its association with socio-demographic, economic, and anthropometric variables, as well as levels of physical activity among undergraduate students. Methods: A cross-sectional study was conducted with 348 undergraduate students at the dining hall of a public Brazilian university located in the state of Mato Grosso do Sul. Body image perception was evaluated using the Silhouette Matching Task. The other variables assessed were sex, age, marital status, housing conditions, socioeconomic […]

Drug therapy problems for patients with tuberculosis and HIV/AIDS at a reference hospital

Natália Helena de Resende ORCID logo , Silvana Spíndola de Miranda ORCID logo , Maria das Graças Braga Ceccato ORCID logo , João Paulo Amaral Haddad ORCID logo , Adriano Max Moreira Reis ORCID logo , Dirce Inês da Silva ORCID logo , [...]

DOI: 10.31744/einstein_journal/2019AO4696

ABSTRACT Objective: To determine the frequency of drug therapy problem in the treatment of patients with tuberculosis and HIV/AIDS. Methods: Data were obtained through a cross-sectional study conducted between September 2015 and December 2016 at a reference hospital in infectious diseases in Belo Horizonte (MG), Brazil. Sociodemographic, clinical, behavioral and pharmacotherapeutic variables were evaluated through a semi-structured questionnaire. Drug-related problems of pharmaceutical care were classified using the Pharmacotherapy Workup method. Factors associated with indication, effectiveness, safety and compliance drug therapy […]

Drug interactions among older adults followed up in a comprehensive medication management service at Primary Care

Tayane Oliveira dos Santos ORCID logo , Mariana Martins Gonzaga do Nascimento ORCID logo , Yone Almeida Nascimento ORCID logo , Grazielli Cristina Batista de Oliveira ORCID logo , Ursula Carolina de Morais Martins ORCID logo , Danielle Fernandes da Silva ORCID logo , [...]

DOI: 10.31744/einstein_journal/2019AO4725

ABSTRACT Objective: To estimate the prevalence of drug interactions and associated factors among older adults followed up in a Comprehensive Medication Management Service at Primary Care. Methods: Firstly, the Beers criteria 2015 was used to define drug interactions; later, drug interactions proposed by Dumbreck for patients with diabetes, depression, and heart failure were evaluated. The associated factors were assessed by univariate (Pearson’s χ2) and multivariate analyses (logistic regression). The significance level of 5% was set for all analyses. Results: The […]

Evaluation of safety, effectiveness and reproducibility of telemedicine for neurosurgical screening

Luiz Adriano Esteves ORCID logo , André Tosta Ribeiro ORCID logo , Elton Gomes da Silva ORCID logo , Marcelo Campos Moraes Amato ORCID logo , Leandro Bôa-Hora Rodrigues ORCID logo , Helder Tedeschi ORCID logo , [...]

DOI: 10.31744/einstein_journal/2019AO4609

ABSTRACT Objective: To ascertain the safety, effectiveness and reproducibility of screening potential neurosurgical patients by means of smartphones. Methods: This is a retrospective and multicentric study. Data were collected from the medical records of patients subjected to real emergency neurosurgical evaluations and compared with assessments by neurosurgeons using smartphones to determine the feasibility of identifying changes in cranial computed tomography scans, potentially serious conditions of patients, and the need for transfer to reference centers. Results: We analyzed 232 cases. The […]

Therapeutic evaluation of magnetic hyperthermia using Fe3O4-aminosilane-coated iron oxide nanoparticles in glioblastoma animal model

Gabriel Nery de Albuquerque Rego ORCID logo , Javier Bustamante Mamani ORCID logo , Taylla Klei Felix Souza ORCID logo , Mariana Penteado Nucci ORCID logo , Helio Rodrigues da Silva ORCID logo , Lionel Fernel Gamarra ORCID logo

DOI: 10.31744/einstein_journal/2019AO4786

ABSTRACT Objective: To evaluate the potential of magnetic hyperthermia using aminosilane-coated superparamagnetic iron oxide nanoparticles in glioblastoma tumor model. Methods: The aminosilane-coated superparamagnetic iron oxide nanoparticles were analyzed as to their stability in aqueous medium and their heating potential through specific absorption rate, when submitted to magnetic hyperthermia with different frequencies and intensities of alternating magnetic field. In magnetic hyperthermia in vitro assays, the C6 cells cultured and transduced with luciferase were analyzed by bioluminescence in the absence/presence of alternating […]

Evaluation and reconditioning of donor organs for transplantation through ex vivo lung perfusion

Luis Gustavo Abdalla ORCID logo , Karina Andrighetti de Oliveira-Braga ORCID logo , Lucas Matos Fernandes ORCID logo , Marcos Naoyuki Samano ORCID logo , Paula Refinetti Camerini ORCID logo , Paulo Manuel Pêgo-Fernandes ORCID logo

DOI: 10.31744/einstein_journal/2019AO4288

ABSTRACT Objective: To assess the feasibility and impact of ex vivo lung perfusion with hyperoncotic solution (Steen Solution™) in the utilization of these organs in Brazil. Methods: In this prospective study, we subjected five lungs considered to be high risk for transplantation to 4 hours of ex vivo lung perfusion, with evaluation of oxygenation capacity. High-risk donor lungs were defined by specific criteria, including inflammatory infiltrates, pulmonary edema and partial pressure of arterial oxygen less than 300mmHg (inspired oxygen fraction […]

Comparative study between monoexponential and biexponential diffusion weighted imaging sequences in multiparametric prostate magnetic resonance imaging

Victor Martins Tonso ORCID logo , Fernando Ide Yamauchi ORCID logo , Thais Caldara Mussi ORCID logo , Eduardo Figueiredo ORCID logo , Ronaldo Hueb Baroni ORCID logo

DOI: 10.31744/einstein_journal/2019AO4615

ABSTRACT Objective: To compare qualitatively and quantitatively, in terms of image quality, a new biexponential diffusion sequence protocol with the standard monoexponential diffusion protocol on multiparametric prostate magnetic resonance imaging. Methods: This study had a prospective data collection and cross-sectional analysis. Between August and November 2017, a total of 70 patients who underwent multiparametric prostate magnetic resonance imaging due to clinical suspicion of prostatic neoplasia were recruited. The images obtained were evaluated by two independent readers regarding subjective/qualitative criteria (six […]

Chronic treatment with hydroalcoholic extract of Plathymenia reticulata promotes islet hyperplasia and improves glycemic control in diabetic rats

Fernanda Oliveira Magalhães ORCID logo , Elizabeth Uber-Bucek ORCID logo , Patricia Ibler Bernardo Ceron ORCID logo , Thiago Fellipe Name ORCID logo , Humberto Eustáquio Coelho ORCID logo , Claudio Henrique Gonçalves Barbosa ORCID logo , [...]

DOI: 10.31744/einstein_journal/2019AO4635

ABSTRACT Objective: To investigate the anti-hyperglycemic effects of Plathymenia reticulata hydroalcoholic extract and related changes in body weight, lipid profile and the pancreas. Methods: Diabetes was induced in 75 adult male Wistar rats via oral gavage of 65mg/Kg of streptozotocin. Rats were allocated to one of 8 groups, as follows: diabetic and control rats treated with water, diabetic and control rats treated with 100mg/kg or 200mg/kg of plant extract, and diabetic and control rats treated with glyburide. Treatment consisted of […]

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