45 results

Effective vancomycin concentrations in children: a cross-sectional study

Geisa Cristina da Silva Alves ORCID logo , Farah Maria Drumond Chequer ORCID logo , Cristina Sanches ORCID logo

DOI: 10.31744/einstein_journal/2019AO4396

ABSTRACT Objective Analyze the microbiological effectiveness, based on the pharmacokinetics/pharmacodynamics correlation of vancomycin in pediatric patients, and to propose dose adjustment. Methods This is an observational, cross-sectional study, conducted in a pediatric hospital, over a 1-year period (2016 to 2017). Children of both sexes, aged 2 to 12 years, were included in the study; burn children, and children in renal replacement therapy were excluded. For the pharmacokinetic analysis, two samples of 2mL of whole blood were collected, respecting the 2-hour […]

Evaluation of the quality of Primary Health Care services for children: reflections on the feasibility of using the Brazilian version of the Primary Care Assessment Tool as a routine assessment tool

Liz Ponnet ORCID logo , Sara Willems ORCID logo , Veerle Vyncke ORCID logo , Aylene Emilia Moraes Bousquat ORCID logo , Ana Luiza d’Ávila Viana ORCID logo , Guilherme Arantes Mello ORCID logo , [...]

DOI: 10.31744/einstein_journal/2019AO4333

ABSTRACT Objective To assess the quality of the Primary Health Care services provided to children and the feasibility of using the Brazilian version of Primary Care Assessment Tool (PCAT-Brazil) as a routine quality assessment tool. Methods A cross-sectional study was carried out in Joanópolis, a small rural town in the State of São Paulo (SP), Brazil. Seven health professionals and 502 caretakers of children using the public health center were interviewed using the PCAT-Brazil, collecting data on the core and […]

Effect of auditory-motor training on auditory processing of school children

Fátima Aparecida Gonçalves ORCID logo , Márcia Ribeiro Vieira ORCID logo , Liliane Desgualdo Pereira ORCID logo

DOI: 10.31744/einstein_journal/2018AO4359

ABSTRACT Objective To compare performance in Avaliação Simplificada do Processamento Auditivo Central and Scale of Auditory Behaviors scores before and after auditory and motor training. Methods Sample comprising 162 children aged 9 to 11 years and attending public schools in the city of São Paulo (SP), Brazil; 122 out of 162 children were allocated to one of three experimental groups: Multisensory; Auditory/Motor and Motor/Auditory. Experimental groups were submitted to 8 hours of auditory, visuospatial and motor stimulation over the course […]

Severe iron-deficiency anemia as initial manifestation of pulmonary hemosiderosis in a child

Natália Noronha ORCID logo , Pedro Ramalho ORCID logo , Rogério Barreira ORCID logo , Juliana Roda ORCID logo , Teresa Reis Silva ORCID logo , Miguel Félix ORCID logo

DOI: 10.31744/einstein_journal/2018RC4505

ABSTRACT Idiopathic pulmonary hemosiderosis is a potentially fatal disease that results from episodes of alveolar hemorrhage of unknown origin. The clinical spectrum is varied, and anemia may constitute the only manifestation of illness, preceding other signs and symptoms by several months. We present the case of a 4 year-old child presenting with fever, vomiting and prostration, associated with pallor. He had microcytic and hypochromic anemia refractory to iron therapy. Gastrointestinal bleeding was ruled out after negative extensive etiological investigation. Subsequently, […]

Helium-oxygen mixture: clinical applicability in an intensive care unit

Milena Siciliano Nascimento ORCID logo , Érica Santos ORCID logo , Cristiane do Prado ORCID logo

DOI: 10.31744/einstein_journal/2018AO4199

ABSTRACT Objective To evaluate if distress respiratory decreases after using helium-oxygen mixture in pediatric patients diagnosed with bronchospasm. Methods This is a retrospective, non-randomized study that included patients diagnosed with bronchospasm, who received a helium-oxygen mixture at three time points (30, 60, and 120 minutes) according to the organization protocol singular, and were admitted to the intensive care unit, from January 2012 to December 2013. This protocol includes patients with bronchospasm who sustained a modified Wood score of moderate to […]

Medications used in pediatric cystic fibrosis population

Stella Pegoraro Alves ORCID logo , Márcia de Azevedo Frank ORCID logo , Denise Bueno ORCID logo

DOI: 10.31744/einstein_journal/2018AO4212

ABSTRACT Objective To describe the drug utilization profile used by pediatric cystic fibrosis patients. Methods A transversal study comprising the analysis of records and interviews with caregivers of pediatric patient in a reference center of Southern Brazil. We collected information about patients’ clinical condition, medication used and household therapy. Results Out of 78 patients participating in the study, prevailing characteristics were: female, self-declared white color, mutation F508del and countryside resident. Forty-three patients had health monitoring exclusively in the hospital’s outpatient […]

Suitability of new drugs registered in Brazil from 2003 to 2013 for pediatric age groups

Jaqueline Cristina da Silveira Xavier e Castro ORCID logo , Stephanie Ferreira Botelho ORCID logo , Taisa Roberta Lopes Machado ORCID logo , Maria Auxiliadora Parreiras Martins ORCID logo , Liliana Batista Vieira ORCID logo , Adriano Max Moreira Reis ORCID logo

DOI: 10.31744/einstein_journal/2018AO4354

ABSTRACT Objective To analyze suitability of new drugs registered in Brazil from 2003 to 2013 for pediatric age groups. Methods A descriptive study of drugs with pediatric indication included in a retrospective cohort of new drugs registered in Brazil. The evaluation of drug suitability for the pediatric age group was performed using the following criteria: suitability of dosage form and capacity to deliver the recommended dose. The drugs were considered adequate for the pediatric age groups when they met both […]

Latent tuberculosis infection and tuberculosis in children and adolescents

Cassia Satsuki Ishikawa ORCID logo , Olivia Mari Matsuo ORCID logo , Flavio Sarno ORCID logo

DOI: 10.1590/S1679-45082018AO4090

ABSTRACT Objective: To describe the characteristics of patients diagnosed with tuberculosis and latent tuberculosis infection. Methods: A retrospective study, between 2012 and 2015, with data from patients of Programa Einstein na Comunidade de Paraisópolis. To evaluate possible factors associated with patient’s sex and diagnoses of tuberculosis and latent tuberculosis infection, χ2 or Fisher’s exact tests were used for qualitative variables, and Mann-Whitney test for quantitative or ordinal qualitative variables. Results: A total of 77 patients were evaluated. Age ranged from […]

Circumcision: postoperative complications that required reoperation

Carolina Talini ORCID logo , Letícia Alves Antunes ORCID logo , Bruna Cecília Neves de Carvalho ORCID logo , Karin Lucilda Schultz ORCID logo , Maria Helena Camargo Peralta Del Valle ORCID logo , Ayrton Alves Aranha Junior ORCID logo , [...]

DOI: 10.1590/S1679-45082018AO4241

ABSTRACT Objective To evaluate post-operative complications of circumcision requiring surgical reintervention. Methods Retrospective analysis of medical records of patients submitted to circumcision from May 1st, 2015 to May 31st, 2016. Results A total of 2,441 circumcisions were performed; in that, 1,940 using Plastibell and 501 by the classic technique. Complications requiring surgical reintervention were found in 3.27% of patients. When separated by surgical technique, 3.4% of circumcisions using Plastibell device required reoperation, as compared to 3% of conventional technique (p=0.79). […]

Clinical and immunohistochemical study of melanotic neuroectodermal tumor of infancy in the maxilla

Hellen Bandeira de Pontes Santos, Aníbal Henrique Barbosa de Luna, Pedro Everton Marques Goes, Alexander Tadeu Sverzut, Cassiano Francisco Weege Nonaka, Pollianna Muniz Alves

DOI: 10.1590/S1679-45082018RC4025

ABSTRACT Melanotic neuroectodermal tumor of infancy is a rare and fast-growing neoplasm. In this study, we describe the case of a 6-month-old female patient, who presented swelling in the anterior maxilla. Tomographic reconstruction showed an unilocular hypodense and expansive area associated with the upper right central primary incisor. The presumptive diagnoses were dentigerous cyst, adenomatoid odontogenic tumor, melanotic neuroectodermal tumor of infancy and rhabdomyosarcoma, and an incisional biopsy was performed. Microscopically, the lesion revealed a biphasic cell population, consisting of […]

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