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Recent Articles

Physical training reverses changes in hepatic mitochondrial diameter of Alloxan-induced diabetic rats

Gabriel Keine Kuga ORCID logo , Rafael Calais Gaspar ORCID logo , Vitor Rosetto Muñoz ORCID logo , Susana Castelo Branco Ramos Nakandakari ORCID logo , Leonardo Breda ORCID logo , Bruna Marina Sandoval ORCID logo , [...]

DOI: 10.1590/S1679-45082018AO4353

ABSTRACT Objective To investigate the effects of physical training on metabolic and morphological parameters of diabetic rats. Methods Wistar rats were randomized into four groups: sedentary control, trained control, sedentary diabetic and trained diabetic. Diabetes mellitus was induced by Alloxan (35mg/kg) administration for sedentary diabetic and Trained Diabetic Groups. The exercise protocol consisted of swimming with a load of 2.5% of body weight for 60 minutes per day (5 days per week) for the trained control and Trained Diabetic Groups, […]

Case-control study of oral disease indexes in individuals with head and neck cancer after antineoplastic therapy

Reyna Aguilar Quispe ORCID logo , Adrielle Lindolpho Cremonesi ORCID logo , Jeanne Kelly Gonçalves ORCID logo , Cassia Maria Fischer Rubira ORCID logo , Paulo Sérgio da Silva Santos ORCID logo

DOI: 10.1590/S1679-45082018AO4245

ABSTRACT Objective To evaluate the oral health of patients with head and neck cancer after antineoplastic treatment, and to compare them with patients with no history of cancer. Methods A total of 75 patients, divided into Study Group, composed of individuals after antineoplastic treatment (n=30), and Control Group, with individuals with no history of cancer (n=45), aged 37 to 79 years. The oral health status was evaluated through the index of decayed, missing or filled permanent teeth (DMFT), community periodontal […]

Oral colonization by Candida species in HIV-positive patients: association and antifungal susceptibility study

Letícia Silveira Goulart ORCID logo , Werika Weryanne Rosa de Souza ORCID logo , Camila Aoyama Vieira ORCID logo , Janaina Sousa de Lima ORCID logo , Ricardo Alves de Olinda ORCID logo , Claudinéia de Araújo ORCID logo

DOI: 10.1590/S1679-45082018AO4224

ABSTRACT Objective To investigate antifungal susceptibility and factors associated with oral colonization by Candida species in HIV-positive patients. Methods A prospective study based on convenience sampling of subjects recruited from a pool of confirmed HIV-positive individuals seen at a specialty outpatient service in Rondonópolis, Mato Grosso, Brazil). Oral swabs were collected from 197 patients. Candida species were identified by standard microbiological techniques (phenotypic and molecular methods). Antifungal susceptibility was investigated using the broth microdilution method. Results A total of 101 […]

Intradetrusor onabotulinumtoxinA injections are significantly more efficacious than oral oxybutynin for treatment of neurogenic detrusor overactivity: results of a randomized, controlled, 24-week trial

Rúiter Silva Ferreira ORCID logo , Carlos Arturo Levi D’Ancona ORCID logo , Matthias Oelke ORCID logo , Maurício Rassi Carneiro ORCID logo

DOI: 10.1590/S1679-45082018AO4207

ABSTRACT Objective To prospectively compare the results of intradetrusor onabotulinumtoxinA injections and oral oxybutynin for urinary continence, urodynamic parameters and quality of life in patients with neurogenic detrusor overactivity due to spinal cord injury. Methods Adult patients under intermittent catheterization were randomized 1:1 to receive one injection of onabotulinumtoxinA 300U or oxybutynin 5mg, per oris, three times/day. Primary study endpoint was change in urinary incontinence episodes/24 hours and secondary study endpoints were maximum cystometric capacity, maximum detrusor pressure, bladder compliance […]

Analysis of the indicators of the Family Health Program in the Metropolitan Region of São Paulo

Paulo Augusto Monteclaro Cesar ORCID logo , Márcia Mello Costa De Liberal ORCID logo , Valdecir Marvulle ORCID logo , Paola Zucchi ORCID logo

DOI: 10.1590/S1679-45082018GS4174

ABSTRACT Objective To analyze the Family Health Program replaced by the Family Health Strategy in 2011, based on health indicators and diseases classified as primary care sensitive. Methods This was a descriptive, analytical and documental study carried out in the Metropolitan Region of São Paulo between 2002 and 2007. We analyzed data from Health observatory for the Metropolitan Region of São Paulo. Pearson’s correlation and the Statistical Package for the Social Sciences software version 17.0 were used to calculate data […]

Erratum: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in diagnosis of mediastinal lesions

DOI: 10.1590/S1679-45082018AO4094E

Ricardo Sales dos Santos1, Marcia Jacomelli1,2, Juliana Pereira Franceschini3, Iunis Suzuki1, Altair da Silva Costa Jr.1,4, Christina Shiang1, Addy Lidvina Mejia Palomino1 1 Hospital Israelita Albert Einstein, São Paulo, SP, Brazil. […]

Current state of multiparameter magnetic resonance imaging of the prostate

Thais Caldara Mussi

DOI: 10.1590/S1679-45082018MD4408

ABSTRACT Magnetic resonance imaging of the prostate is an imaging method that has shown increasing relevance in urological practice. Due to technological evolution of scanners and the introduction of functional sequences, it has enabled greater accuracy in detection and characterization of prostate tumors.

Challenge, Discussion and Conclusion: an active teaching strategy to turn traditional lectures into collaborative classes

Welbert Oliveira Pereira, Fernanda Teresa Lima

DOI: 10.1590/S1679-45082018ED4362

D2R: step by step Just as with other active strategies, a D2R interactive class requires some pillars that enable preparing the students (therefore it is necessary to provide study material in advance), group projects (it is fundamental to divide the students into teams before class), and practical application of the content (the teacher prepares and presents cases and issues that simulate the practical application of the class, avoiding the valid question of students “Why do I need to learn this?”). […]

Formulation, implementation and evaluation of a distance course for accreditation in patient safety

Poliana Nunes Wanderlei, Erik Montagna

DOI: 10.1590/S1679-45082018GS4316

ABSTRACT Objective To formulate and to implement a virtual learning environment course in patient safety, and to propose ways to estimate the impact of the course in patient safety outcomes. Methods The course was part of an accreditation process and involved all employees of a public hospital in Brazil. The whole hospital staff was enrolled in the course. The accreditation team defined the syllabus. The education guidelines were divided into 12 modules related to quality, patient safety and required organizational […]