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Chemokines and immunity

Diana Carolina Torres Palomino, Luciana Cavalheiro Marti

DOI: 10.1590/S1679-45082015RB3438

Chemokines are a large family of small cytokines and generally have low molecular weight ranging from 7 to 15kDa. Chemokines and their receptors are able to control the migration and residence of all immune cells. Some chemokines are considered pro-inflammatory, and their release can be induced during an immune response at a site of infection, while others are considered homeostatic and are involved in controlling of cells migration during tissue development or maintenance. The physiologic importance of this family of […]