5 results

Brazilian Nutritional Consensus in Hematopoietic Stem Cell Transplantation: Elderly

Sandra Elisa Adami Batista Gonçalves ORCID logo , Andreza Alice Feitosa Ribeiro ORCID logo , Erika Yuri Hirose ORCID logo , Fabio Pires de Souza Santos ORCID logo , Flávia Munhoz Ferreira ORCID logo , Ludmila de Oliveira Muniz Koch ORCID logo , [...]

DOI: 10.31744/einstein_journal/2019AE4340

ABSTRACT The Brazilian Nutritional Consensus in Hematopoietic Stem Cell Transplantation: Elderly was elaborated by nutritionists, nutrologists and hematologists physicians from 15 Brazilians reference centers in hematopoietic stem cell transplantation, in order to emphasize the importancy of nutritional status and the body composition during the treatment, as well as the main characteristics related to patient’s nutritional assessment. Establishing the consensus, we intended to improve and standardize the nutritional therapy during the hematopoietic stem cell transplantation. The Consensus was approved by the […]

Cardiovascular risk and use of conicity index in patients submitted to autologous hematopoietic stem cell transplantation

Suelyne Rodrigues de Morais, Ana Carolina Cavalcante Viana, Ana Filomena Camacho Santos Daltro, Priscila da Silva Mendonça

DOI: 10.1590/S1679-45082018AO4253

ABSTRACT Objective To analyze the prevalence of overweight and the use of conicity index for cardiovascular risk assessment in individuals submitted to autologous hematopoietic stem cell transplantation. Methods The sample comprised 91 patients of both sexes, who underwent autologous hematopoietic stem cell transplantation from September 2008 to December 2013, aged 18 years or over. To determine the nutritional profile, we collected anthropometric data on weight, height, waist circumference upon hospital admission. The body mass index and the conicity index were […]

Histopathologic diagnosis of chronic graft-versus-host disease of the oral mucosa according to the National Institutes of Health Consensus

Paulo Sérgio da Silva Santos, Fábio Luiz Coracin, José Carlos de Almeida Barros, Marina Helena Cury Gallottini

DOI: 10.1590/S1679-45082014AO2974

ObjectiveTo validate the minimal criteria of the histopathologic diagnosis of oral chronic graft-versus-host disease, based on the histopathologic classification of the National Institutes of Health and correlate them with clinical features.MethodsForty-one specimens containing both oral mucosa and salivary glands were analyzed in slides stained with hematoxylin-eosin. The histological specimens were blindly examined by two trained pathologists using criteria recommended for the histopathologic diagnosis of chronic graft-versus-host disease proposed by the National Institutes of Health Consensus. The clinical classification of chronic […]

Allogeneic hematopoietic stem cell transplantation in children with primary immunodeficiencies: Hospital Israelita Albert Einstein experience

Juliana Folloni Fernandes, Fabio Rodrigues Kerbauy, Andreza Alice Feitosa Ribeiro, Jose Mauro Kutner, Luis Fernando Aranha Camargo, Adalberto Stape, [...]

DOI: 10.1590/S1679-45082011AO2007

ABSTRACT Objective: To report the experience of a tertiary care hospital with allogeneic hematopoietic stem cell transplantation in children with primary immunodeficiencies. Methods: Seven pediatric patients with primary immunodeficiencies (severe combined immunodeficiency: n = 2; combined immunodeficiency: n = 1; chronic granulomatous disease: n = 1; hyper-IgM syndrome: n = 2; and IPEX syndrome: n = 1) who underwent eight hematopoietic stem cell transplants in a single center, from 2007 to 2010, were studied. Results: Two patients received transplants from […]

Current management of severe acquired aplastic anemia

Phillip Scheinberg

DOI: 10.1590/S1679-45082011RW2156

ABSTRACT Overall survival in severe aplastic anemia has markedly improved in the past four decades due to advances in stem cell transplantation, immunosuppressive therapies and supportive care. Horse anti-thymocyte globulin plus cyclosporine is the standard immunosuppressive regimen in severe aplastic anemia, and often employed as initial therapy as most are not candidates for a matched related stem cell transplantation. With this regimen, hematologic response can be achieved in 60 to 70% of cases, but relapse is observed in 30 to […]