10 results

Cardiac tissue engineering: current state-of-the-art materials, cells and tissue formation

Isabella Caroline Pereira Rodrigues ORCID logo , Andreas Kaasi ORCID logo , Rubens Maciel Filho ORCID logo , André Luiz Jardini ORCID logo , Laís Pellizzer Gabriel ORCID logo

DOI: 10.1590/S1679-45082018RB4538

ABSTRACT Cardiovascular diseases are the major cause of death worldwide. The heart has limited capacity of regeneration, therefore, transplantation is the only solution in some cases despite presenting many disadvantages. Tissue engineering has been considered the ideal strategy for regenerative medicine in cardiology. It is an interdisciplinary field combining many techniques that aim to maintain, regenerate or replace a tissue or organ. The main approach of cardiac tissue engineering is to create cardiac grafts, either whole heart substitutes or tissues […]

Cardiovascular risk and use of conicity index in patients submitted to autologous hematopoietic stem cell transplantation

Suelyne Rodrigues de Morais, Ana Carolina Cavalcante Viana, Ana Filomena Camacho Santos Daltro, Priscila da Silva Mendonça

DOI: 10.1590/S1679-45082018AO4253

ABSTRACT Objective To analyze the prevalence of overweight and the use of conicity index for cardiovascular risk assessment in individuals submitted to autologous hematopoietic stem cell transplantation. Methods The sample comprised 91 patients of both sexes, who underwent autologous hematopoietic stem cell transplantation from September 2008 to December 2013, aged 18 years or over. To determine the nutritional profile, we collected anthropometric data on weight, height, waist circumference upon hospital admission. The body mass index and the conicity index were […]

Association of subclinical inflammation, glycated hemoglobin and risk for obstructive sleep apnea syndrome

Carolina Vicaria Rodrigues D’Aurea, Bruno Gion de Andrade Cerazi, Antonio Gabriele Laurinavicius, Carolina Castro Porto Silva Janovsky, Raquel Dilguerian de Oliveira Conceição, Raul D Santos, [...]

DOI: 10.1590/S1679-45082017AO3900

ABSTRACT Objective To investigate the inter-relation between high sensitivity C-reactive protein and glycated hemoglobin in prediction of risk of obstructive sleep apnea. Methods We included all individuals participating in a check-up program at the Preventive Medicine Center of Hospital Israelita Albert Einstein in 2014. The Berlin questionnaire for risk of obstructive sleep apnea was used, and the high sensitivity C-reactive protein and glycated hemoglobin levels were evaluated. Results The sample included 7,115 participants (age 43.4±9.6 years, 24.4% women). The Berlin […]

Heart rate variability based on risk stratification for type 2 diabetes mellitus

Julia Silva-e-Oliveira, Pâmela Marina Amélio, Isabela Lopes Laguardia Abranches, Dênis Derly Damasceno, Fabianne Furtado

DOI: 10.1590/S1679-45082017AO3888

ABSTRACT Objective To evaluate heart rate variability among adults with different risk levels for type 2 diabetes mellitus. Methods The risk for type 2 diabetes mellitus was assessed in 130 participants (89 females) based on the questionnaire Finnish Diabetes Risk Score and was classified as low risk (n=26), slightly elevated risk (n=41), moderate risk (n=27) and high risk (n=32). To measure heart rate variability, a heart-rate monitor Polar S810i® was employed to obtain RR series for each individual, at rest, […]

Agreement in cardiovascular risk rating based on anthropometric parameters

Endilly Maria da Silva Dantas, Cristiane Jordânia Pinto, Rodrigo Pegado de Abreu Freitas, Anna Cecília Queiroz de Medeiros

DOI: 10.1590/S1679-45082015AO3349

ObjectiveTo investigate the agreement in evaluation of risk of developing cardiovascular diseases based on anthropometric parameters in young adults.MethodsThe study included 406 students, measuring weight, height, and waist and neck circumferences. Waist-to-height ratio and the conicity index. The kappa coefficient was used to assess agreement in risk classification for cardiovascular diseases. The positive and negative specific agreement values were calculated as well. The Pearson chi-square (χ2) test was used to assess associations between categorical variables (p

Check-up and cardiovascular risk progression: is there a room for innovation?

Raquel Dilguerian de Oliveira Conceição, Antonio Gabriele Laurinavicius, Nea Miwa Kashiwagi, José Antonio Maluf de Carvalho, Carlos Alberto Garcia Oliva, Raul Dias Santos Filho

DOI: 10.1590/S1679-45082015AO3216

ABSTRACTObjective:To evaluate the impact of traditional check-up appointment on the progression of the cardiovascular risk throughout time.Methods:This retrospective cohort study included 11,126 medical records of asymptomatic executives who were evaluated between January, 2005 and October, 2008. Variables included participants’ demographics characteristics, smoking habit, history of cardiovascular diseases, diabetes, dyslipidemia, total cholesterol, HDL, triglycerides, glucose, c-reactive protein, waist circumference, hepatic steatosis, Framingham score, metabolic syndrome, level of physical activity, stress, alcohol consumption, and body mass index.Results:A total of 3,150 patients was […]

Relevance of prehypertension as a diagnostic category in asymptomatic adults

Fernando Costa Nary, Raul D. Santos, Antonio Gabriele Laurinavicius, Raquel Dilguerian de Oliveira Conceição, José Antonio Maluf de Carvalho

DOI: 10.1590/S1679-45082013000300008

Objective:To assess the association of prehypertension with metabolic, inflammatory and cardiovascular risk profile in asymptomatic individuals.METHODS:Between 2006 and 2009, 11,011 asymptomatic adults (mean age: 43 years; 22% females), underwent a check-up protocol. They were divided into 3 groups: normotensive group (arterial pressure=120/80mmHg), prehypertensive group (arterial pressure >120/80mmHg and 140/90mmHg or prior diagnosis of hypertension). Each group metabolic and cardiovascular group profile was assessed.RESULTS:The prevalence of normotension, prehypertension and hypertension was 27.9%, 53.9% and 18.2%, respectively. Prehypertensive individuals were older (mean […]

Evaluating compliance to a cardiac rehabilitation program in a private general hospital

Vanessa Mair, Ana Paula Breda, Marcos Eduardo Boquembuzo Nunes, Luciana Diniz Nagem Janot de Matos

DOI: 10.1590/S1679-45082013000300004

Objective:Identify the primary factors that influenced the participant in our cardiovascular rehabilitation program towards missing their therapy sessions, and to correlate those factors with age, cardiovascular risk, and motivation of our population.METHODS:We conducted a retrospective study with 42 patients (69.15±13.93 years) participating in the cardiac rehabilitation program at a general hospital in São Paulo, through the analysis of two scales applied during the initial evaluation: Cardiac Rehabilitation Barriers Scale and scale of the original provision. We used Spearman correlation to […]

Elderly women with metabolic syndrome present higher cardiovascular risk and lower relative muscle strength

Darlan Lopes Farias, Ramires Alsamir Tibana, Tatiane Gomes Teixeira, Denis César Leite Vieira, Vitor Tarja, Dahan da Cunha Nascimento, [...]

DOI: 10.1590/S1679-45082013000200007

Objective:To compare the metabolic, anthropometric, arterial blood pressure, and muscle strength parameters of elderly women with and without metabolic syndrome.METHODS:A case-control study with 27 (67.3±4.8 years of age, 31.0±5.0kg/m²) elderly women with metabolic syndrome and 33 (68.8±5.6 years of age, 27.2±5.3kg/m²) sedentary control elderly women. They were submitted to an evaluation of body composition by means of dual-energy X-ray absorptiometry and muscle strength testing with 10 maximal repetitions of knee extension.RESULTS:When compared to the elderly women without metabolic syndrome, those […]

Assessment of cardiovascular risk of patients with arterial hypertension of a public health unit

Evandro José Cesarino, André Luiz Gomes Vituzzo, Julliane Messias Cordeiro Sampaio, Danilo Avelar Sampaio Ferreira, Heloísa Andrião Ferreira Pires, Luiz de Souza

DOI: 10.1590/S1679-45082012000100008

Objective:To assess the cardiovascular risk, using the Framingham risk score, in a sample of hypertensive individuals coming from a public primary care unit.METHODS:The caseload comprised hypertensive individuals according to criteria established by the JNC VII, 2003, of 2003, among 1601 patients followed up in 1999, at the Cardiology and Arterial Hypertension Outpatients Clinic of the Teaching Primary Care Unit, at the Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo. The patients were selected by draw, aged over 20 […]