3 results

Medications used in pediatric cystic fibrosis population

Stella Pegoraro Alves ORCID logo , Márcia de Azevedo Frank ORCID logo , Denise Bueno ORCID logo

DOI: 10.31744/einstein_journal/2018AO4212

ABSTRACT Objective To describe the drug utilization profile used by pediatric cystic fibrosis patients. Methods A transversal study comprising the analysis of records and interviews with caregivers of pediatric patient in a reference center of Southern Brazil. We collected information about patients’ clinical condition, medication used and household therapy. Results Out of 78 patients participating in the study, prevailing characteristics were: female, self-declared white color, mutation F508del and countryside resident. Forty-three patients had health monitoring exclusively in the hospital’s outpatient […]

Strategies for appropriate antibiotic use in intensive care unit

Camila Delfino Ribeiro da Silva, Moacyr Silva Júnior

DOI: 10.1590/S1679-45082015RW3145

The comsumption of antibiotics is high, mainly in intensive care units. Unfortunately, most are inappropriately used leading to increased multi-resistant bacteria. It is well known that initial empirical therapy with broad-spectrum antibiotics reduce mortality rates. However the prolonged and irrational use of antimicrobials may also increase the risk of toxicity, drug interactions and diarrhea due to Clostridium difficile. Some strategies to rational use of antimicrobial agents include avoiding colonization treatment, de-escalation, monitoring serum levels of the agents, appropriate duration of […]

Implementation and progress of clinical pharmacy in the rational medication use in a large tertiary hospital

Fábio Teixeira Ferracini, Silvana Maria de Almeida, Juliana Locatelli, Sandra Petriccione, Celina Setsuko Haga

DOI: 10.1590/s1679-45082011ao2140

ABSTRACTObjective:To show developments and contributions of a clinical pharmacy service in safety and rational use of medications in a large tertiary hospital.Methods:Clinical pharmacists were responsible for all issues using medications at the hospital. In the beginning this professional was responsible for analyzing medical prescriptions, horizontal visits, and to set up protocols. Afterwards, other activities were designated such as monitoring for drug safety, participating in committees and managed routines. If problems were found, the pharmacist reported them for the physician and, […]