All publications of “Rubens Maciel Filho”

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Cardiac tissue engineering: current state-of-the-art materials, cells and tissue formation

Isabella Caroline Pereira Rodrigues ORCID logo , Andreas Kaasi ORCID logo , Rubens Maciel Filho ORCID logo , André Luiz Jardini ORCID logo , Laís Pellizzer Gabriel ORCID logo

DOI: 10.1590/S1679-45082018RB4538

ABSTRACT Cardiovascular diseases are the major cause of death worldwide. The heart has limited capacity of regeneration, therefore, transplantation is the only solution in some cases despite presenting many disadvantages. Tissue engineering has been considered the ideal strategy for regenerative medicine in cardiology. It is an interdisciplinary field combining many techniques that aim to maintain, regenerate or replace a tissue or organ. The main approach of cardiac tissue engineering is to create cardiac grafts, either whole heart substitutes or tissues […]