8 results

Clinical characteristics and long-term progression of young patients with acute coronary syndrome in Brazil

Alexandre de Matos Soeiro, Felipe Lourenço Fernandes, Maria Carolina Feres de Almeida Soeiro, Carlos Vicente Serrano Jr, Múcio Tavares de Oliveira Jr

DOI: 10.1590/S1679-45082015AO3381

ObjectiveIn Brazil, there are few descriptions in the literature on the angiographic pattern and clinical characteristics of young patients with acute coronary syndrome, despite the evident number of cases in the population. The objective of this study was to evaluate which clinical characteristics are most closely related to the acute coronary syndrome in young patients, and what long-term outcomes are in this population.MethodsThis is a prospective observational study with 268 patients aged under 55 years with acute coronary syndrome, carried […]

Acute management of unstable angina and non-ST segment elevation myocardial infarction

Fernando Morita Fernandes Silva, Antonio Eduardo Pereira Pesaro, Marcelo Franken, Mauricio Wajngarten

DOI: 10.1590/S1679-45082015RW3172

Non-ST segment elevation coronary syndrome usually results from instability of an atherosclerotic plaque, with subsequent activation of platelets and several coagulation factors. Its treatment aims to reduce the ischemic pain, limiting myocardial damage and decreasing mortality. Several antiplatelet and anticoagulation agents have been proven useful, and new drugs have been added to the therapeutic armamentarium in the search for higher anti-ischemic efficacy and lower bleeding rates. Despite the advances, the mortality, infarction and readmission rates remain high.

Cells involved in extracellular matrix remodeling after acute myocardial infarction

Larissa Ferraz Garcia, Fábio D’Aguiar Mataveli, Ana Maria Amaral Antônio Mader, Thérèse Rachell Theodoro, Giselle Zenker Justo, Maria Aparecida da Silva Pinhal

DOI: 10.1590/S1679-45082015AO2970

ObjectiveEvaluate the effects of VEGF165 gene transfer in the process of remodeling of the extracellular matrix after an acute myocardial infarct.MethodsWistar rats were submitted to myocardial infarction, after the ligation of the left descending artery, and the left ventricle ejection fraction was used to classify the infarcts into large and small. The animals were divided into groups of ten, according to the size of infarcted area (large or small), and received or not VEGF165 treatment. Evaluation of different markers was […]

Very late stent thrombosis with bare-metal stent: identifying severe stent malapposition and underexpansion by intravascular ultrasound

Adriano Caixeta, Vanessa Cristina Salomon Palma Braga, Gary S Mintz

DOI: 10.1590/S1679-45082013000300017

A 60-year-old man with a history of implantation of two bare-metal stents 2 years prior presented to the emergency department with new-onset chest pain. He has been regularly taking angiotensinconverting enzyme inhibitors, beta blockers and aspirin. Aspirin was suspended for 10 days prior to the current hospitalization in order to perform surgery to remove a kidney tumor. He underwent coronary angiography, which revealed a right coronary artery with a distal intraluminal defect within the stents, suggesting thrombus. Intravascular ultrasound demonstrated […]

Contrast echocardiography in myocardial infarction

Maria Luciana Zacarias Hannouche da Trindade, Marcelo Luiz Campos Vieira, Ana Clara Tude Rodrigues, Miguel José Francisco Neto, Claudio Henrique Fischer, Samira Saady Morhy

DOI: 10.1590/S1679-45082013000300023

The contrast agents used in ultrasound are approved for several clinical situations. New echocardiographic techniques, such as harmonic imaging and power pulse inversion imaging, can improve the visualization of microbubbles. In this article we discuss the early development of contrast echocardiography, new technologies that help improve image acquisition and its practical role in the assessment of myocardial infarction.

Effect of implementing an acute myocardial infarction guideline on quality indicators

Marcia Makdisse, Marcelo Katz, Alessandra da Graça Corrêa, Luciano Monte Alegre Forlenza, Marco Antonio Perin, Fábio Sândoli de Brito Júnior, [...]

DOI: 10.1590/S1679-45082013000300016

Objective:To evaluate the compliance rates to quality of care indicators along the implementation of an acute myocardial infarction clinical practice guideline.METHODS:A clinical guideline for acute myocardial infarction was introduced on March 1st, 2005. Patients admitted for acute myocardial infarction from March 1st, 2005 to December 31st, 2012 (n=1,431) were compared to patients admitted for acute myocardial infarction before the implementation of the protocol (n=306). Compliance rates to quality of care indicators (ASA prescription on hospital admission and discharge, betablockers on […]

Depressive symptoms in patients with acute coronary syndrome

Aline Pardo de Mello, Antonio Carlos de Camargo Carvalho, Elisa Mieko Suemitsu Higa

DOI: 10.1590/s1679-45082011ao1721

ABSTRACTObjective:To trace an epidemiological profile, to verify presence of depressive symptoms in patients with previous diagnosis of acute coronary syndrome and to identify factors that contribute to maintenance of depressive symptoms in the sample. Methods:A cross-section study carried out at the Cardiology Outpatients Clinics of Universidade Federal de São Paulo. An instrument prepared by the authors was used, which was based on similar studies with patient identification data, questions related to the psychological follow-up, relationship with family members and friends, […]

Relation between three-dimensional and two-dimensional echocardiography and biochemical analysis in patients with ST-segment elevation myocardial infarction percutaneously treated

Marcelo Luiz Campos Vieira, Wercules Antônio Oliveira, Alexandre Ferreira Cury, Adriana Cordovil, Ana Clara Tude Rodrigues, Gustavo Alberto Frazatto Naccarato, [...]

DOI: 10.1590/s1679-45082010ao1438

ABSTRACTObjective:The prognosis of patients with acute myocardial infarction depends on multiple features that can demonstrate myocardial injury degree (such as serum markers of cardiac necrosis), and also on adaptive mechanisms relative to the acute event. The aim of the study was to assess the relation between biochemical and echocardiographic findings from three-dimensional echocardiographic (3D Echo) analysis and echocardiographic two-dimensional (2D Echo) left ventricular ejection fraction in patients with ST-segment elevation acute myocardial infarction, submitted to primary percutaneous treatment.Methods:A prospective study […]