All publications of “Ana Maria Amaral Antônio Mader”

2 results

Histological analysis of the repair of dural lesions with silicone mesh in rats subjected to experimental lesions

Fernando William Figueiredo da Rosa, Pedro Henrique Isoldi Pohl, Ana Maria Amaral Antônio Mader, Carla Peluso de Paiva, Aline Amaro dos Santos, Bianca Bianco, [...]

DOI: 10.1590/S1679-45082015AO3378

ABSTRACTObjective To evaluate inflammatory reaction, fibrosis and neovascularization in dural repairs in Wistar rats using four techniques: simple suture, bovine collagen membrane, silicon mesh and silicon mesh with suture.Methods Thirty Wistar rats were randomized in five groups: the first was the control group, submitted to dural tear only. The others underwent durotomy and simple suture, bovine collagen membrane, silicon mesh and silicon mesh with suture. Animals were euthanized and the spine was submitted to histological evaluation with a score system […]

Cells involved in extracellular matrix remodeling after acute myocardial infarction

Larissa Ferraz Garcia, Fábio D’Aguiar Mataveli, Ana Maria Amaral Antônio Mader, Thérèse Rachell Theodoro, Giselle Zenker Justo, Maria Aparecida da Silva Pinhal

DOI: 10.1590/S1679-45082015AO2970

ObjectiveEvaluate the effects of VEGF165 gene transfer in the process of remodeling of the extracellular matrix after an acute myocardial infarct.MethodsWistar rats were submitted to myocardial infarction, after the ligation of the left descending artery, and the left ventricle ejection fraction was used to classify the infarcts into large and small. The animals were divided into groups of ten, according to the size of infarcted area (large or small), and received or not VEGF165 treatment. Evaluation of different markers was […]