All publications of “Giselle Zenker Justo”

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Cells involved in extracellular matrix remodeling after acute myocardial infarction

Larissa Ferraz Garcia, Fábio D’Aguiar Mataveli, Ana Maria Amaral Antônio Mader, Thérèse Rachell Theodoro, Giselle Zenker Justo, Maria Aparecida da Silva Pinhal

DOI: 10.1590/S1679-45082015AO2970

ObjectiveEvaluate the effects of VEGF165 gene transfer in the process of remodeling of the extracellular matrix after an acute myocardial infarct.MethodsWistar rats were submitted to myocardial infarction, after the ligation of the left descending artery, and the left ventricle ejection fraction was used to classify the infarcts into large and small. The animals were divided into groups of ten, according to the size of infarcted area (large or small), and received or not VEGF165 treatment. Evaluation of different markers was […]