5 results

Expanding the pool of kidney donors: use of kidneys with acute renal dysfunction

Ana Cristina Carvalho de Matos, Lúcio Roberto Requião-Moura, Gabriela Clarizia, Marcelino de Souza Durão Junior, Eduardo José Tonato, Rogério Chinen, [...]

DOI: 10.1590/S1679-45082015RW3147

ABSTRACTGiven the shortage of organs transplantation, some strategies have been adopted by the transplant community to increase the supply of organs. One strategy is the use of expanded criteria for donors, that is, donors aged >60 years or 50 and 59 years, and meeting two or more of the following criteria: history of hypertension, terminal serum creatinine >1.5mg/dL, and stroke as the donor´s cause of death. In this review, emphasis was placed on the use of donors with acute renal […]

Lung transplantation

José Eduardo Afonso Júnior, Eduardo de Campos Werebe, Rafael Medeiros Carraro, Ricardo Henrique de Oliveira Braga Teixeira, Lucas Matos Fernandes, Luis Gustavo Abdalla, [...]

DOI: 10.1590/S1679-45082015RW3156

ABSTRACTLung transplantation is a globally accepted treatment for some advanced lung diseases, giving the recipients longer survival and better quality of life. Since the first transplant successfully performed in 1983, more than 40 thousand transplants have been performed worldwide. Of these, about seven hundred were in Brazil. However, survival of the transplant is less than desired, with a high mortality rate related to primary graft dysfunction, infection, and chronic graft dysfunction, particularly in the form of bronchiolitis obliterans syndrome. New […]

Pancreas transplantation: review

Roberto Ferreira Meirelles Júnior, Paolo Salvalaggio, Alvaro Pacheco-Silva

DOI: 10.1590/S1679-45082015RW3163

ABSTRACTVascularized pancreas transplantation is the only treatment that establishes normal glucose levels and normalizes glycosylated hemoglobin levels in type 1 diabetic patients. The first vascularized pancreas transplant was performed by William Kelly and Richard Lillehei, to treat a type 1 diabetes patient, in December 1966. In Brazil, Edison Teixeira performed the first isolated segmental pancreas transplant in 1968. Until the 1980s, pancreas transplants were restricted to a few centers of the United States and Europe. The introduction of tacrolimus and […]

Liver-specific magnetic resonance contrast medium in the evaluation of chronic liver disease

Marcio Augusto Correia Rodrigues dos Reis, Ronaldo Hueb Baroni

DOI: 10.1590/S1679-45082015RW3159

ABSTRACTThe hepatobiliary-specific contrast medium (gadoxetic acid – Primovist®) is primarily used to improve detection and characterization of focal hepatic lesions, such as in chronic liver disease patients with suspected hepatocellular carcinoma. Since the contrast medium is selectively taken up by functioning hepatocytes in the late hepatobiliary phase, it helps to detect typical hepatocellular carcinoma, which show low signal intensity on this phase. This imaging feature also assists in differentiating regenerative/dysplastic nodules from early hepatocellular carcinomas (with over 90% accuracy), as […]

Heart transplantation: review

Sandrigo Mangini, Bárbara Rubim Alves, Odílson Marcos Silvestre, Philippe Vieira Pires, Lucas José Tachotti Pires, Milena Novaes Cardoso Curiati, [...]

DOI: 10.1590/S1679-45082015RW3154

ABSTRACTHeart transplantation is currently the definitive gold standard surgical approach in the treatment of refractory heart failure. However, the shortage of donors limits the achievement of a greater number of heart transplants, in which the use of mechanical circulatory support devices is increasing. With well-established indications and contraindications, as well as diagnosis and treatment of rejection through defined protocols of immunosuppression, the outcomes of heart transplantation are very favorable. Among early complications that can impact survival are primary graft failure, […]