Highlights ■ First Brazilian Portuguese version of the LT-QOL questionnaire. ■ Translation and cross-cultural adaptation followed COSMIN recommendations. ■ Strong internal consistency (Cronbach’s alpha=0.86). ■ Excellent intra-rater reliability (ICC=0.93). ■ High convergent validity with SF-36 and good correlation  with SGRQ. ■ Provides a disease-specific tool for assessing quality of life after lung transplantation in Brazil. ■ Supports future clinical monitoring and research on transplant outcomes. ABSTRACT Objective: To translate, cross-culturally adapt, and validate the Lung Transplant Quality of Life questionnaire […]

ABSTRACT Objective: To assess the feasibility and impact of ex vivo lung perfusion with hyperoncotic solution (Steen Solution™) in the utilization of these organs in Brazil. Methods: In this prospective study, we subjected five lungs considered to be high risk for transplantation to 4 hours of ex vivo lung perfusion, with evaluation of oxygenation capacity. High-risk donor lungs were defined by specific criteria, including inflammatory infiltrates, pulmonary edema and partial pressure of arterial oxygen less than 300mmHg (inspired oxygen fraction […]

ABSTRACT Lung transplantation is a globally accepted treatment for some advanced lung diseases, giving the recipients longer survival and better quality of life. Since the first transplant successfully performed in 1983, more than 40 thousand transplants have been performed worldwide. Of these, about seven hundred were in Brazil. However, survival of the transplant is less than desired, with a high mortality rate related to primary graft dysfunction, infection, and chronic graft dysfunction, particularly in the form of bronchiolitis obliterans syndrome. […]