Highlights ■ Cow’s milk oral immunotherapy maintained desensitization over five years. ■ Anaphylactic reactions were more frequent during the first maintenance year. ■ The risk of eosinophilic esophagitis persisted throughout follow-up. ■ Continuous monitoring for allergic reactions and esophagitis symptoms is required. ABSTRACT Objective: To describe the long-term outcomes of patients undergoing oral immunotherapy for cow’s milk allergy in a pediatric allergy clinic, focusing on treatment efficacy and adverse reactions over 5 years of follow-up. Methods: This retrospective cohort study […]