Highlights ■ Immunohistochemistry distinguishes Warthin-like mucoepidermoid carcinoma from metaplastic Warthin tumor. ■ CK7, mitochondrial patterns, and double-layer epithelium suggest metaplastic Warthin tumor. ■ Basal CK14, CK5/6, and p63 distinguish metaplastic Warthin tumor from Warthin-like mucoepidermoid carcinoma. ABSTRACT Objective: This study aimed to analyze the clinicopathological and immunohistochemical profiles of unconventional Warthin tumors and mucoepidermoid carcinomas. Methods: Eleven low-grade salivary gland tumors with Warthin-like features were analyzed. Group A (n=6) showed a double-layered oncocytic epithelium in less than 50% of the […]

Highlights ■ Oxidative stress markers are associated with the intensity and consequences of ischemia-reperfusion injury during deceased-donor kidney transplantation. ■ The donor’s serum hydrogen peroxide level achieved 85.7% sensitivity and a 91.7% negative predictive value for  detecting delayed graft function lasting more than one week. ■ Donor H2O2 ≤14μM is suggested to dichotomize risk for delayed graft function lasting longer than a week. ■ This study provides pivotal information on the use of oxidative stress markers to identify patients at […]

Highlights ■ Forty-four percent of mothers of children with autism spectrum disorder have poor sleep quality. ■ Seventy percent did not meet the recommended 7-9 hours of sleep. ■ Demographic, child-related, and clinical data were associated with sleep problems. ABSTRACT Objective: To analyze the factors associated with sleep quality and duration in mothers of children with autism spectrum disorder. Methods: A cross-sectional study was conducted with 595 mothers (37±7yrs) of children and adolescents with autism spectrum disorder (8.1±3.1yrs). The assessed […]

Highlights ■ Transoral robotic surgery applied in patients with T1–T2 oropharyngeal and laryngeal tumors. ■ Mean hospital stay: 2.1 days. ■ Minimal postoperative complications. ■ 5-year survival: 77%, with comparable cost-effectiveness. ABSTRACT Objective: To assess the feasibility and benefits of transoral robotic surgery in the public healthcare system and to conduct a cost analysis of its implementation. Methods: This prospective, nonrandomized, observational cohort study was conducted over 24 months and included patients with T1-T2 oropharyngeal and supraglottic laryngeal tumors. Results: […]

Highlights ■ All standard echocardiographic views were obtained in the prone position. ■ In the prone position, 16 of 17 key variables were consistently acquired. ■ Image quality was slightly reduced only in the parasternal view. ■ Quantitative measurements were comparable between the prone and supine positions. ABSTRACT Objective: Transthoracic echocardiography is essential for hemodynamic assessment in critically ill patients; however, its use in the prone position remains challenging. This study aimed to assess the feasibility of performing transthoracic echocardiography […]

Highlights ■ Mammary hypertrophy was not associated with postoperative totally implantable venous access device catheter tip displacement. ■ Upright and supine chest radiography with a radiopaque ruler allowed precise quantification of catheter tip displacement. ■ Non-deforming chest wall surgery and a history of peripherally inserted central catheters history were significantly associated with catheter tip migration. ABSTRACT Objective: This study aimed to evaluate the change in the position of totally implantable venous access devices in patients with mammary hypertrophy compared to […]

Highlights ■ High vaccine coverage correlated with sharp declines in the incidence of pediatric meningitis C. ■ The incidence fell by 98% by 2021 following national introduction of the MenC vaccine. ■ Vaccine coverage dropped after 2015, aligned with the rising cases observed in 2022. ■ MenC vaccination significantly reduced morbidity and mortality nationwide. ABSTRACT Objective: To analyze the correlation between vaccination coverage against meningitis C and epidemiological indicators of morbidity and mortality associated with the disease in Brazilian pediatric […]

Highlights ■ Carbapenem resistance rose sharply during the COVID-2019 pandemic, doubling from 2019 to 2020, while infection control practices prevented proportional increases in  healthcare-associated infections. ■ Genomic analyses revealed high diversity among blaKPC-positive isolates, with an expansion of sequence types and a predominance of sporadic non-outbreak clones throughout the pandemic period. ■ Shifts in mobile genetic elements and virulence markers occurred during the pandemic, including the emergence of the integrative and conjugative element of Klebsiella pneumoniae ICEKp4, changes in O-antigen […]

Highlights ■ The Brazilian Portuguese version of the Sexual Risk Behaviors Scale has strong measurement properties, including content validity, structural validity, and internal consistency. ■ The Sexual Risk Behaviors Scale showed measurement invariance between females and males and sufficient test-retest reliability, supporting its stability and applicability across sexes. ■ The Sexual Risk Behaviors Scale is a valid and reliable instrument for assessing sexual risk behaviors among university students in Brazil. Abstract Objective: This study aimed to translate and evaluate the […]

Highlights ■ Smartphone-based training improved functional capacity in older adults. ■ Remote and in-person supervision led to similar gains in functional capacity. ■ Postural balance improved comparably in both groups. ■ Lower limb strength improved only in-person supervision with exercise App. ABSTRACT Introduction: Population aging is a significant global challenge, demanding strategies that promote healthy aging. Regular physical activity is crucial for maintaining functional capacity, quality of life, and preventing chronic diseases in older adults. However, sedentary behavior remains high, […]