Highlights ■ High vaccine coverage correlated with sharp declines in the incidence of pediatric meningitis C. ■ The incidence fell by 98% by 2021 following national introduction of the MenC vaccine. ■ Vaccine coverage dropped after 2015, aligned with the rising cases observed in 2022. ■ MenC vaccination significantly reduced morbidity and mortality nationwide. ABSTRACT Objective: To analyze the correlation between vaccination coverage against meningitis C and epidemiological indicators of morbidity and mortality associated with the disease in Brazilian pediatric […]