16 results

Prevalence of renal insufficiency in elderly cancer patients in a tertiary cancer center

Lucíola de Barros Pontes, Yuri Philippe Pimentel Vieira Antunes, Diogo Diniz Gomes Bugano, Theodora Karnakis, Auro del Giglio, Rafael Aliosha Kaliks

DOI: 10.1590/s1679-45082014ao3003

Objective To estimate the prevalence of abnormal glomerular filtration rate in elderly patients with solid tumors.Methods A retrospective study with patients aged >65 years diagnosed with solid tumors between January 2007 and December 2011 in a cancer center. The following data were collected: sex, age, serum creatinine at the time of diagnosis and type of tumor. Renal function was calculated using abbreviated Modification of Diet in Renal Disease (MDRD) formulae and then staged in accordance with the clinical practice guidelines […]

Acceptance of hospital diets and nutritional status among inpatients with cancer

Daiane Ferreira, Tessa Gomes Guimarães, Aline Marcadenti

DOI: 10.1590/S1679-45082013000100008

Objective:To verify acceptance of hospital diets as to the nutritional status among patients admitted to the Oncology/Hematology Unit of a tertiary care hospital.METHODS:A cross-sectional study conducted among 100 patients, aged >18 years, of both genders. Body mass index and subjective global nutritional evaluation by patients were used to detect the nutritional status. The rest-ingestion index was used to evaluate diet acceptance, and the reasons for non-acceptance were identified by means of a questionnaire. Data were expressed in means and standard […]

Is there publication bias towards Brazilian articles on cancer?

Luiz Victor Maia Loureiro, Donato Callegaro Filho, Altieres de Arruda Rocha, Bernard Lobato Prado, Taciana Sousa Mutão, Carlos del Cistia Donnarumma, [...]

DOI: 10.1590/S1679-45082013000100005

Objective:To investigate whether Brazilian articles on cancer are published in journals with an impact factor and/or repercussion (measured by the number of citations) inferior to those that come from foreign organizations.METHODS:A search was carried out in PubMed for the MeSH term “neoplasm” with the limits clinical trial, affiliation of the Brazilian author(s), and interval from July 1st, 2009 to June 30, 2010. Selected for matching were non-Brazilian related articles published from three months prior to three months after the date […]

Interventional procedures for cancer pain management

Fabiola Peixoto Minson, Fabrício Dias Assis, Thais Kfouri Vanetti, Jamir Sardá Junior, Wanessa Pereira Mateus, Auro Del Giglio

DOI: 10.1590/S1679-45082012000300006

Objective:To describe types of interventional medical procedures its rationale use and benefits for a population with cancer assisted at a private hospital in São Paulo.METHODS:Quantitative and descriptive cross-sectional study using data from patients submitted to interventional procedures between 2007 and 2008. We used descriptive and inferential statistics (frequency, mean, and t-test) to analyze data.RESULTS:A total of 137 patients were submitted to interventional procedures for pain and, out of this total, 14 mentioned cancer-related pain. The mean pain intensity was 7.1 […]

The importance of a database in the management of healthcare services

Cláudia Toledo de Andrade, Ana Maria Prado Castello Branco Magedanz, Daísa Mesquita Escobosa, Wellington Martins Tomaz, Carolina Sampieri Santinho, Tania Oliveira Lopes, [...]

DOI: 10.1590/S1679-45082012000300018

Objective:To present the epidemiological profile of cancer patients belonging to a database of a Hospital Cancer Registry and to report on the importance of this database in managing healthcare services at an Oncology and Hematology Center.METHODS:A retrospective survey conducted with 1617 records of patients diagnosed with cancer at the institution between 2004 and 2009. The types of cancer analyzed were of the colon and rectum, breast, prostate and lung. The variables used in the study were age, gender, stage of […]

Apoptosis and in vivo models to study the molecules related to this phenomenon

Adriana Luchs, Claudia Pantaleão

DOI: 10.1590/S1679-45082010RB1685

ABSTRACT Apoptosis or programmed cell death is a physiological process, essential for eliminating cells in excess or that are no longer necessary to the organism, acting on tissue homeostasis, although the phenomenon is also involved in pathological conditions. Apoptosis promotes activation of biochemical pathways inside cells called caspase pathway, of the proteins responsible for the cleavage of several cell substrates, leading to cell death. Antiapoptotic members of the Bcl-2 family (B cell CLL/lymphoma 2), that belong to the intrinsic route […]

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