einstein (São Paulo). 01/Jan/2010;8(1):117-21.

Autoimmune uveitis: study of treatment therapies

Alessandra Gonçalves , Luciana de Deus Vieira de , Denise Vilarinho , Rubens Belfort , Osvaldo Augusto , Luiz Vicente

DOI: 10.1590/S1679-45082010RB1416

ABSTRACT

Experimental autoimmune uveitis is an organ-specific T-cell mediated autoimmune disease characterized by inflammation and consequent destruction of the neural retina and adjacent tissues. Inflammation in experimental autoimmune uveitis may be induced in rodents by immunization with retinal antigens, such as interphotoreceptor retinoid-binding protein. We present a review of experimental studies that correlate primary immunobiological functions with this chronic disease and the possible use of molecules for the treatment of autoimmune uveitis.

Autoimmune uveitis: study of treatment therapies
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