ABSTRACT Case report of a patient with severe atopic dermatitis who showed a good response to dupilumab. She had already used two immunosuppressive agents, cyclosporine A and mycophenolate mofetil, for the treatment of atopic dermatitis with no proper control of the disease. She had also been taking all measures to control severe cases of the disease: bath and environmental controls, topical potent corticosteroids and emollients. She presented constant pruritus and skin lesions, frequent skin infections e poor quality of life. […]

ABSTRACT Endovascular aneurysm repair is an established technique for treating many infrarenal aortic aneurysms. Infection is one of the most serious complications of this technique, and although percutaneous treatment has been well established for intra-abdominal collections, its use to treat peri-prosthetic fluid collections has not been well determined. In this article we describe a small series of three patients who were treated with percutaneous drainage, with good clinical and imaging responses. Percutaneous drainage is a safe, effective and minimally invasive […]

ABSTRACT Vesicouterine fistula is a rare condition. Its incidence, however, has been increasing due to the higher incidence of cesarean sections. The presence of a live fetus inside the bladder who passed through a vesicouterine fistula is an extremely rare situation. We report a case of woman who underwent two previous cesarean sections, was referred to a hospital due to mild pelvic pain and genital bleeding. At the moment, physical examination was normal. Ultrasound scan revealed a gestational sac inserted […]

ABSTRACT Ligneous conjunctivitis is a rare form of chronic and recurrent bilateral conjunctivitis, in which thick membranes develop on the tarsal conjunctiva and on other mucosae. We report the case of a 55-year old female patient with bilateral ligneous conjunctivitis who was successfully treated with 50% heterologous serum. There was no recurrence or side effects after one-year follow-up. We suggest the use of 50% heterologous serum should be further studied to better determine its efficacy as a treatment option for […]

ABSTRACT Epidermolysis bullosa describes a group of skin conditions caused by mutations in genes encoding proteins related to dermal-epidermal adhesion. In the United States, 50 cases of epidermolysis bullosa per 1 million live births are estimated, 92% of which classified as simplex, 5% dystrophic, 1% junctional and 2% non-classified. Dystrophic epidermolysis bullosa is associated with autosomal, dominant and recessive inheritance. Epidermolysis bullosa causes severe psychological, economic and social impacts, and there is currently no curative therapy, only symptom control. Embryonic […]

ABSTRACT The left ventricular noncompaction is a congenital cardiomyopathy characterized by the presence of abnormal trabeculations in the left ventricle. The present study describes the case of a 14-year-old female Para athlete, who plays goalball. She was asymptomatic, with history of congenital nystagmus and mild visual impairment, who presented nonspecific electrocardiographic abnormalities during pre-competition screening. Cardiac magnetic resonance imaging showed left ventricular non-compaction (non-compacted to compacted layer ratio equal to 2.5) and mild biventricular systolic dysfunction. Initially, the patient was […]

ABSTRACT Oral squamous papilloma is a benign tumor whose pathogenesis has been associated with human papillomavirus infection. Thus, it is noteworthy that human papillomavirus infection is one of the risk factors associated with the development of cervical, anogenital, pharynx, larynx and oral cavity carcinomas. Oral squamous papilloma can affect any region of the oral cavity, and transmission of human papillomavirus can occur by direct contact, sexual intercourse or from mother to child during delivery. The diagnosis is clinical and histopathological, […]

A 75-year old female patient presenting chronic arterial hypertension, was admitted at the emergency department with moderate unspecific abdominal pain. A computed tomography of total abdomen with no contrast enhancement was requested due to altered renal function and suspicion of acute obstructive abdomen. The computed tomography sections ( and ) showed a fusiform aneurysm in the aortoiliac bifurcation, extending up to the right iliac artery. This aneurysm was causing erosion of the anterior aspect of L4 vertebral body, with bone […]

Idiopathic masseter muscle hypertrophy is a rare condition, characterized by unilateral or bilateral enlargement of this muscle, sometimes associated to mandibular angle exostosis.() Its etiology is unknown, and there is a possible relation with unilateral masticatory activity, dental malocclusion, temporomandibular joint dysfunction, bruxism, or emotional alterations.(,) The diagnosis is made primarily based on the clinical presentation, complemented with ultrasound and, if required, magnetic resonance imaging.() It is important to make differential diagnoses with tumors or inflammatory processes in muscles, bones […]

A 15-day-old female newborn presenting nasal obstruction since birth underwent computed tomography of the paranasal sinuses in our department due to clinical suspicion of choanal atresia. The patient presented no other complaints. Computed tomography () allowed the diagnosis of pyriform aperture stenosis, which is a rare cause of nasal obstruction in neonates and was first described in 1989.() Pyriform aperture stenosis becomes particularly significant during the first two months of life when infants are mandatory nose breathers. […]