2 results
28/May/2026
28/May/2026
DOI: 10.31744/einstein_journal/2026AO2153
Highlights ■ Colorectal carcinoma originates from within cancer stem cells of the large intestine. ■ Tissue levels of ALDH1-2 and LGR5 proteins were associated with greater tumor aggressiveness. ■ Discovery of signaling pathways can improve cancer treatments that control cancer stem cells. ABSTRACT Objective: To investigate the association of CD44, CD133, ALDH1-2, and LGR5 expression with clinicopathological tumor variables. Methods: Twenty-eight adult patients with colorectal carcinoma who underwent curative surgery were included in the study. Paraffin-embedded samples were subjected to […]
Keywords: Biomarkers, tumor; Colonic neoplasms; Colorectal neoplasms; Immunohistochemistry; Neoplasm metastasis; Neoplastic stem cells; Rectal neoplasms
07/Nov/2023
DOI: 10.31744/einstein_journal/2023RC0544
ABSTRACT Tailgut cysts are rare congenital lesions that are remnants of the embryonic hindgut. This abnormality presents with non-specific symptoms or no symptoms; therefore, misdiagnosis is common. Here, we present four cases of tailgut cysts that were successfully removed using a robotic surgical approach. A 42-year-old woman with tenesmus, pain in the right gluteal region, and discomfort in the rectal region during evacuation was referred to our medical center. Another patient was a 28-year-old woman who presented with the same […]
Keywords: Congenital abnormalities; Cysts; Margins of excision; Rectal neoplasms; Robotic surgical procedures