ABSTRACT Circulatory shock is a common fatal condition. Despite this, information on this syndrome in the current medical literature is fragmented and esoteric. Adherence to each basic element of care can have a profound impact on patient outcomes. Disturbances in pumping (cardiogenic), content/container relationship (hypovolemic and vasoplegic), or blockage in blood circulation (obstructive) can induce tissue hypoperfusion, causing hemodynamic shock. If not quickly reversed, hypoperfusion progresses to irreversible multi-organ failure. The course can be fatal even before reaching this stage […]

Highlights Gradient Boosting Machine and Random Forest models were built for prediction of mortality at cardiac intensive care units. A total of 9,761 intensive care unit stays of patients admitted under a Cardiac Surgery and Cardiac Medical services were studied. The AUROC and AUPRC values were significantly superior to seven conventional systems compared. The machine learning models’ calibration curves were substantially closer to the ideal line. ABSTRACT Objective: Logistic Regression has been used traditionally for the development of most predictor […]

Highlights A  single-center study evaluated the prevalence and risk factors for Burnout syndrome in intensive care unit teams. The study revealed a high prevalence of Burnout syndrome in at least one dimension. Factors such as profession and having two or more jobs were associated with severe burnout symptoms. The study highlighted the need for interventions and support to address burnout among intensive care unit teams. ABSTRACT Objective: To evaluate the prevalence of burnout among the intensive care unit team of […]

Highlights Acute respiratory distress syndrome is a severe presentation of COVID-19 without effective treatment despite intensive research. Inhaled nitric oxide is a vasodilator that has been studied in patients with acute respiratory distress syndrome COVID-19 yielding contradictory results. The use of inhaled nitric oxide rescue therapy in critically ill patients with COVID-19 experiencing moderate-to-severe acute respiratory distress syndrome was significantly associated with an improvement in oxygenation parameters with no difference in mortality. ABSTRACT Objective: To evaluate the responsiveness of COVID-19 […]

ABSTRACT Objective To review the long-term outcomes (functional status and psychological sequelae) of survivors of critical illnesses due to epidemic viral pneumonia before the COVID-19 pandemic and to establish a benchmark for comparison of the COVID-19 long-term outcomes. Methods This systematic review of clinical studies reported the long-term outcomes in adults admitted to intensive care units who were diagnosed with viral epidemic pneumonia. An electronic search was performed using databases: MEDLINE®, Web of Science™, LILACS/IBECS, and EMBASE. Additionally, complementary searches […]

Highlights Worse outcomes were more prevalent in the teaching hospital. Understanding the importance of teaching hospitals to implement well-established care protocols is critical.   INTRODUCTION Some studies have reported the association between receiving hospital characteristics and the number of patients assisted with clinical outcomes.(,) Some authors have also demonstrated this relationship in scenarios such as coronary care units and care units for patients with diabetes.(,) Reportedly, hospitals with high admission volumes have better outcomes for surgical procedures; however, studies on […]

Highlights 43.4% of the cohort developed acute kidney injury. D-dimer and fibrinogen levels were high in both groups. Rotational thromboelastometry data were similar between groups. Serum levels of antithrombin activity and protein C were lower in patients who developed acute kidney injury. Objective The incidence of thrombotic events and acute kidney injury is high in critically ill patients with COVID-19. We aimed to evaluate and compare the coagulation profiles of patients with COVID-19 developing acute kidney injury versus those who […]

Highlights Two artificial neural networks, type of multilayer perceptron, and a random forest model were developed. Multilayer perceptron and random forest were compared to the OASIS, SAPS, SAPS II, SAPS III, LODS, SOFA, and EVCI Scores. Discrimination was assessed with the receiver operator characteristic and precision-recall curves. Calibration of the predictive models was evaluated with the Brier Score. ABSTRACT Objective The variation in mortality rates of intensive care unit oncological patients may imply that clinical characteristics and prognoses are very […]

Highlights We compared characteristics between patients admitted during the first and second waves. There were 1,427 intensive care unit patients with COVID-19: 421 (first wave) and 1,006 (second wave). The patients in the second wave were younger and less severely ill at the time of intensive care unit admission. Patients exhibited similar mortality rates and need for invasive organ support. ABSTRACT Objective To describe and compare the clinical characteristics and outcomes of patients admitted to intensive care units during the […]

ABSTRACT Objective: To report the experience of performing bronchoscopy in patients who underwent supportive therapy with extracorporeal membrane oxygenation in whom the bronchoscopy was performed. Methods: This was a review of medical records of patients diagnosed with extracorporeal membrane oxygenation and who required diagnostic or therapeutic bronchoscopy. Records included were related to patients admitted to the intensive care unit of Hospital das Clínicas of Faculdade de Medicina of Universidade de São Paulo, between 2014 and 2020. Results: During the study, […]