20/Aug/2024
Prevalence and risk factors of Burnout syndrome among intensive care unit members during the second wave of COVID-19: a single-center study
einstein (São Paulo). 20/Aug/2024;22:eAO0271.
View Article20/Aug/2024
Prevalence and risk factors of Burnout syndrome among intensive care unit members during the second wave of COVID-19: a single-center study
DOI: 10.31744/einstein_journal/2024AO0271
Highlights A single-center study evaluated the prevalence and risk factors for Burnout syndrome in intensive care unit teams. The study revealed a high prevalence of Burnout syndrome in at least one dimension. Factors such as profession and having two or more jobs were associated with severe burnout symptoms. The study highlighted the need for interventions and support to address burnout among intensive care unit teams. ABSTRACT Objective: To evaluate the prevalence of burnout among the intensive care unit team of […]
Keywords: Anxiety; Burnout, psychological; COVID-19; Intensive care units; Pandemics; Stress, psychological; Surveys and questionnaires
29/Jul/2024
Inhaled nitric oxide in moderate-to-severe COVID-19 acute respiratory distress syndrome: a retrospective cohort study
einstein (São Paulo). 29/Jul/2024;22:eAO0578.
View Article29/Jul/2024
Inhaled nitric oxide in moderate-to-severe COVID-19 acute respiratory distress syndrome: a retrospective cohort study
DOI: 10.31744/einstein_journal/2024AO0578
Highlights Acute respiratory distress syndrome is a severe presentation of COVID-19 without effective treatment despite intensive research. Inhaled nitric oxide is a vasodilator that has been studied in patients with acute respiratory distress syndrome COVID-19 yielding contradictory results. The use of inhaled nitric oxide rescue therapy in critically ill patients with COVID-19 experiencing moderate-to-severe acute respiratory distress syndrome was significantly associated with an improvement in oxygenation parameters with no difference in mortality. ABSTRACT Objective: To evaluate the responsiveness of COVID-19 […]
Keywords: Coronavirus infections; COVID-19; Critical illness; Intensive care units; Length of stay; Nitric oxide; Respiratory distress syndrome; SARS-CoV-2
01/Mar/2024
Long-term outcomes for epidemic viral pneumonia survivors after discharge from the intensive care unit: a systematic review
einstein (São Paulo). 01/Mar/2024;22(spe1):eRW0352.
View Article01/Mar/2024
Long-term outcomes for epidemic viral pneumonia survivors after discharge from the intensive care unit: a systematic review
DOI: 10.31744/einstein_journal/2024RW0352
ABSTRACT Objective To review the long-term outcomes (functional status and psychological sequelae) of survivors of critical illnesses due to epidemic viral pneumonia before the COVID-19 pandemic and to establish a benchmark for comparison of the COVID-19 long-term outcomes. Methods This systematic review of clinical studies reported the long-term outcomes in adults admitted to intensive care units who were diagnosed with viral epidemic pneumonia. An electronic search was performed using databases: MEDLINE®, Web of Science™, LILACS/IBECS, and EMBASE. Additionally, complementary searches […]
Keywords: Coronavirus infections; Epidemics; Influenza A virus, H1N1 subtype; Intensive care units; Middle east respiratory syndrome coronavirus; Mortality; Pneumonia, viral; Quality of life; Respiratory distress syndrome; Return to work; Treatment outcomes
15/Sep/2023
Are patient volume and care level in teaching hospitals variables affecting clinical outcomes in adult intensive care units?
einstein (São Paulo). 15/Sep/2023;21:eAO0406.
View Article15/Sep/2023
Are patient volume and care level in teaching hospitals variables affecting clinical outcomes in adult intensive care units?
DOI: 10.31744/einstein_journal/2023AO0406
Highlights Worse outcomes were more prevalent in the teaching hospital. Understanding the importance of teaching hospitals to implement well-established care protocols is critical. INTRODUCTION Some studies have reported the association between receiving hospital characteristics and the number of patients assisted with clinical outcomes.(,) Some authors have also demonstrated this relationship in scenarios such as coronary care units and care units for patients with diabetes.(,) Reportedly, hospitals with high admission volumes have better outcomes for surgical procedures; however, studies on […]
Keywords: Critical care; Hospitals, teaching; Intensive care units; Patients; Treatment outcome
30/Aug/2023
COVID-19-associated coagulopathy and acute kidney injury in critically ill patients
DOI: 10.31744/einstein_journal/2023AO0119
Highlights 43.4% of the cohort developed acute kidney injury. D-dimer and fibrinogen levels were high in both groups. Rotational thromboelastometry data were similar between groups. Serum levels of antithrombin activity and protein C were lower in patients who developed acute kidney injury. Objective The incidence of thrombotic events and acute kidney injury is high in critically ill patients with COVID-19. We aimed to evaluate and compare the coagulation profiles of patients with COVID-19 developing acute kidney injury versus those who […]
Keywords: Acute kidney injury; Blood coagulation; Coronavirus infections; COVID-19; Intensive care units; SARS-CoV-2; Thrombosis
28/Aug/2023
Outcome prediction for critical care patients with respiratory neoplasms using a multilayer perceptron neural network
einstein (São Paulo). 28/Aug/2023;21:eAO0071.
View Article28/Aug/2023
Outcome prediction for critical care patients with respiratory neoplasms using a multilayer perceptron neural network
DOI: 10.31744/einstein_journal/2023AO0071
Highlights Two artificial neural networks, type of multilayer perceptron, and a random forest model were developed. Multilayer perceptron and random forest were compared to the OASIS, SAPS, SAPS II, SAPS III, LODS, SOFA, and EVCI Scores. Discrimination was assessed with the receiver operator characteristic and precision-recall curves. Calibration of the predictive models was evaluated with the Brier Score. ABSTRACT Objective The variation in mortality rates of intensive care unit oncological patients may imply that clinical characteristics and prognoses are very […]
Keywords: Artificial neural network; Hospital mortality; Intensive care units; Respiratory tract neoplasms; Survival
Clinical characteristics and outcomes of patients with COVID-19 admitted to the intensive care unit during the first and second waves of the pandemic in Brazil: a single-center retrospective cohort study

05/Jul/2023
Clinical characteristics and outcomes of patients with COVID-19 admitted to the intensive care unit during the first and second waves of the pandemic in Brazil: a single-center retrospective cohort study
einstein (São Paulo). 05/Jul/2023;21:eAO0233.
View Article05/Jul/2023
Clinical characteristics and outcomes of patients with COVID-19 admitted to the intensive care unit during the first and second waves of the pandemic in Brazil: a single-center retrospective cohort study
DOI: 10.31744/einstein_journal/2023AO0233
Highlights We compared characteristics between patients admitted during the first and second waves. There were 1,427 intensive care unit patients with COVID-19: 421 (first wave) and 1,006 (second wave). The patients in the second wave were younger and less severely ill at the time of intensive care unit admission. Patients exhibited similar mortality rates and need for invasive organ support. ABSTRACT Objective To describe and compare the clinical characteristics and outcomes of patients admitted to intensive care units during the […]
Keywords: Coronavirus infections; COVID-19; Critical care outcomes; Extracorporeal membrane oxygenation; Intensive care units; Mortality; Noninvasive ventilation; Respiration artificial; SARS-CoV-2
20/May/2022
Flexible broncoscopy in patients in supportive therapy with oxygenation by extracorporeal membrane
DOI: 10.31744/einstein_journal/2022AO6666
ABSTRACT Objective: To report the experience of performing bronchoscopy in patients who underwent supportive therapy with extracorporeal membrane oxygenation in whom the bronchoscopy was performed. Methods: This was a review of medical records of patients diagnosed with extracorporeal membrane oxygenation and who required diagnostic or therapeutic bronchoscopy. Records included were related to patients admitted to the intensive care unit of Hospital das Clínicas of Faculdade de Medicina of Universidade de São Paulo, between 2014 and 2020. Results: During the study, […]
Keywords: Bronchoscopy; Extracorporeal membrane oxygenation; Intensive care units; Respiratory distress syndrome
07/Mar/2022
Needs of family members of patients in a coronary care unit
DOI: 10.31744/einstein_journal/2022AO6258
ABSTRACT Objective: To identify the need of family members of patients hospitalized in a coronary intensive care unit and their degree of satisfaction with the care provided. Methods: An observational and cross-sectional study including family members of patients hospitalized in the coronary intensive care unit for acute coronary syndrome in Killip I or II. After the second visit of the same family member to the patient in the unit, a 43-item inventory of needs and stressors of family members was […]
Keywords: Acute coronary syndrome; Critical care; Family; Humanization of assistance; Inpatients; Intensive care units; Nursing; Patient-centered care
Clinical characteristics and outcomes of COVID-19 patients admitted to the intensive care unit during the first year of the pandemic in Brazil: a single center retrospective cohort study

22/Nov/2021
Clinical characteristics and outcomes of COVID-19 patients admitted to the intensive care unit during the first year of the pandemic in Brazil: a single center retrospective cohort study
einstein (São Paulo). 22/Nov/2021;19:eAO6739.
View Article22/Nov/2021
Clinical characteristics and outcomes of COVID-19 patients admitted to the intensive care unit during the first year of the pandemic in Brazil: a single center retrospective cohort study
DOI: 10.31744/einstein_journal/2021AO6739
ABSTRACT Objective: To describe clinical characteristics, resource use, outcomes, and to identify predictors of in-hospital mortality of patients with COVID-19 admitted to the intensive care unit. Methods: Retrospective single-center cohort study conducted at a private hospital in São Paulo (SP), Brazil. All consecutive adult (≥18 years) patients admitted to the intensive care unit, between March 4, 2020 and February 28, 2021 were included in this study. Patients were categorized between survivors and non-survivors according to hospital discharge. Results: During the […]
Keywords: Betacoronavirus; Coronavirus; Coronavirus infections; COVID-19; Critical care outcomes; Extracorporeal membrane oxygenation; Intensive care units; Mortality; Noninvasive ventilation; Respiration artificial; SARS-CoV-2