2 results

Should we treat fever in critically ill patients? A summary of the current evidence from three randomized controlled trials

Ary Serpa Neto, Victor Galvão Moura Pereira, Giancarlo Colombo, Farah Christina de la Cruz Scarin, Camila Menezes Souza Pessoa, Leonardo Lima Rocha

DOI: 10.1590/S1679-45082014RW2785

Fever is a nonspecific response to various types of infectious or non-infectious insult and its significance in disease remains an enigma. Our aim was to summarize the current evidence for the use of antipyretic therapy in critically ill patients. We performed systematic review and meta-analysis of publications from 1966 to 2013. The MEDLINE and CENTRAL databases were searched for studies on antipyresis in critically ill patients. The meta-analysis was limited to: randomized controlled trials; adult human critically ill patients; treatment […]

Serum soluble-Fas is a predictor of red blood cell transfusion in critically ill patients

Ilana Levy Korkes, Gustavo Schvartsman, Ilson Jorge Lizuka, Beata Marie Quinto, Maria Aparecida Dalboni, Maria Eugênia Canziani, [...]

DOI: 10.1590/S1679-45082013000400012

Objective:To investigate the relation between the need for red blood cell transfusion and serum levels of soluble-Fas, erythropoietin and inflammatory cytokines in critically ill patients with and without acute kidney injury.METHODS:We studied critically ill patients with acute kidney injury (n=30) and without acute kidney injury (n=13), end-stage renal disease patients on hemodialysis (n=25) and healthy subjects (n=21). Serum levels of soluble-Fas, erythropoietin, interleukin 6, interleukin 10, iron status, hemoglobin and hematocrit concentration were analyzed in all groups. The association between […]