The journal einstein (São Paulo) – e-ISSN 2317-6385 is dedicated to dissemination of high-quality scientific content that advances our understanding of human disease with the goal of improving prevention, care, diagnostics and treatment of patients globally.
Transcranial sonography has become a useful tool in the differential diagnosis of parkinsonian syndromes. This is a non-invasive, low cost procedure. The main finding on transcranial sonography in patients with idiopathic Parkinson’s disease is an increased echogenicity of the mesencephalic substantia nigra region. This hyperechogenicity is present in more than 90% of cases, and reflects a dysfunction in the dopaminergic nigrostriatal pathway. This study discussed how the hyperechogenicity of the substantia nigra may facilitate the differential diagnosis of parkinsonian syndromes.
Bor-Seng-Shu,Edson and Pedroso,José Luiz and Andrade,Daniel Ciampi de and Barsottini,Orlando Graziani Povoas and Andrade,Luiz Augusto Franco de and Barbosa,Egberto Reis and Teixeira,Manoel Jacobsen. Transcranial sonography in Parkinson’s disease. Einstein (São Paulo) [online]. 2012, vol. 10, n. 2, [cited 2025-09-06], pp.242-246. Available from: <https://journal.einstein.br/article/transcranial-sonography-in-parkinsons-disease/>. ISSN 1679-4508. https://doi.org/10.1590/S1679-45082012000200022