All publications of “José Luiz Pedroso”

2 results

Sneddon’s syndrome: case report and review of its relationship with antiphospholipid syndrome

Livia Almeida Dutra, Pedro Braga-Neto, José Luiz Pedroso, Orlando Graziani Povoas Barsottini

DOI: 10.1590/S1679-45082012000200018

The Sneddon’s syndrome is a rare disorder characterized by the occurrence of cerebrovascular disease associated with livedo reticularis. The antiphospholipid syndrome is the most frequent type of acquired thrombophilia, defined by the occurrence of thrombosis or pregnancy morbidity in the presence of persistently positive antiphospholipid antibodies. Approximately 80% of Sneddon’s syndrome patients have an antiphospholipid antibody marker. These antibodies may play a pathogenetic role in some cases of Sneddon’s syndrome, and many authors consider these two syndromes as the same […]

Transcranial sonography in Parkinson’s disease

Edson Bor-Seng-Shu, José Luiz Pedroso, Daniel Ciampi de Andrade, Orlando Graziani Povoas Barsottini, Luiz Augusto Franco de Andrade, Egberto Reis Barbosa, [...]

DOI: 10.1590/S1679-45082012000200022

Transcranial sonography has become a useful tool in the differential diagnosis of parkinsonian syndromes. This is a non-invasive, low cost procedure. The main finding on transcranial sonography in patients with idiopathic Parkinson’s disease is an increased echogenicity of the mesencephalic substantia nigra region. This hyperechogenicity is present in more than 90% of cases, and reflects a dysfunction in the dopaminergic nigrostriatal pathway. This study discussed how the hyperechogenicity of the substantia nigra may facilitate the differential diagnosis of parkinsonian syndromes.