All publications of “Edson Bor-Seng-Shu”

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Transcranial sonography in Parkinson’s disease

Edson Bor-Seng-Shu, José Luiz Pedroso, Daniel Ciampi de Andrade, Orlando Graziani Povoas Barsottini, Luiz Augusto Franco de Andrade, Egberto Reis Barbosa, [...]

DOI: 10.1590/S1679-45082012000200022

Transcranial sonography has become a useful tool in the differential diagnosis of parkinsonian syndromes. This is a non-invasive, low cost procedure. The main finding on transcranial sonography in patients with idiopathic Parkinson’s disease is an increased echogenicity of the mesencephalic substantia nigra region. This hyperechogenicity is present in more than 90% of cases, and reflects a dysfunction in the dopaminergic nigrostriatal pathway. This study discussed how the hyperechogenicity of the substantia nigra may facilitate the differential diagnosis of parkinsonian syndromes.