einstein (São Paulo). 28/May/2026;24:eAO1673.
Omission of sentinel lymph node biopsy in breast cancer: a survey of Brazilian breast surgeons
DOI: 10.31744/einstein_journal/2026AO1673
INTRODUCTION
Sentinel lymph node biopsy (SLNB) is used to assess axillary involvement in patients with early-stage breast cancer and clinically node-negative axillae. In the late twentieth century, SLNB replaced axillary lymph node dissection after randomized trials demonstrated similar survival rates but lower morbidity.(,)
Over the last few years, new advances have resulted in the de-escalation of axillary surgery. A randomized clinical trial with a 10-year follow-up period (ACOSOG Z0011) evaluated the omission of axillary lymph node dissection in patients with early-stage breast cancer, clinically node-negative axillae, and up to two positive axillary sentinel lymph nodes undergoing breast-conserving treatment and radiation therapy and the study found similar overall survival and local recurrence rates between patients who underwent axillary dissection and those who did not.()
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