Highlights ■ The extract, transform, and load algorithm automates data extraction and updates in the PostgreSQL database. ■ The interactive dashboard enables detailed queries on establishments and professionals. ■ Results highlight medical doctor deficit in 22 cities and a shortage of community agents. ■ The tool can scale and assist managers in resource allocation for healthcare. ABSTRACT Objective: To develop a process (pipeline) for extracting, processing, and analyzing data from the National Registry of Health Establishments in the State of […]

Highlights ■ The 52 Oncology Nurse Navigator Core Competencies, across five categories, were cross-culturally adapted. ■ The competencies outline oncology nurse navigator’s role in Brazil. Objective: This study aimed to translate and cross-culturally adapt the Oncology Nurse Navigator Core Competencies 2017 instrument into Brazilian Portuguese. Methods: This study used a methodological cross-cultural adaptation approach. After authorization from the authors of the original version of the Oncology Nurse Navigator Core Competencies 2017 comprising 52 competencies, the instrument was translated following the […]

Highlights ■ Different vegetable peptones have different amino acid compositions. ■ Different peptones produce different crop responses. ■ Peptone composition can be compared to that of fetal bovine serum. ■ Vegetable peptones can replace fetal bovine serum. ABSTRACT Objective: This study aimed to evaluate the effects of different concentrations of vegetable peptones (pea, wheat, and soy) as substitutes for fetal bovine serum in stem cell cultures derived from human exfoliated deciduous teeth. Methods: Stem cell cultures derived from human exfoliated […]

Highlights ■ In this study, mice were exposed to music at the intrauterine stage. ■ Music exposure before aversive memory formation enhances neuroplasticity, aiding in extinction. ■ The recall test showed that music exposure had sustained beneficial long-term effects. ABSTRACT Objective: This study aimed to analyze the influence of Mozart’s Sonata K.448 on contextual memory extinction in male mice. Methods: Male mice were divided into three groups (G1-Mozart, G2-Ambience, G3-Control). Throughout the project, only the first group was exposed to […]

Highlights ■ Matching methodologies may reduce bias in economic evaluations. ■ Liver transplantation within the Proadi-SUS context has an incremental cost-effectiveness ratio below the Health Technology Incorporation in the Brazilian Health System threshold. ■ The patients who received transplant had a median survival of 10.1 years after list enrollment. ■ The mean cost per transplanted patient was US$ PPP 162,821.96. ABSTRACT Objective: To estimate the incremental cost and survival of patients on the liver transplantation waiting list who were referred […]

Highlights ■ Family presence improves communication and patient comfort during pediatric emergency room care. ■ Overall, 90.2% of companions stayed during care, despite 71% being unaware of the legislation. ■ Of the professionals, 96% allowed companions, with 87% citing comfort for patients. ■ This study supports creating clear protocols for family inclusion during emergencies. ABSTRACT Objective: To evaluate the perceptions of family companions and the professional team regarding the presence of a family member during emergency and urgent care at […]

Highlights ■ Clinical deterioration is a global concern related to patient safety. ■ The Pediatric Alert Score includes assessments of neurological, respiratory, and cardiovascular conditions; temperature; and urine output. ■ The Pediatric Alert Score demonstrated high reliability and strong validity with the B-PEWS-Br. ■ The Pediatric Alert Score is a reliable tool for detecting clinical deterioration and improving patient safety. ABSTRACT Objective: To evaluate the construct validity and reliability of the Pediatric Alert Score in hospitalized children and adolescents. Methods: […]

Highlights ■ Prevalence of HPV16 is extremely low in the tonsil of healthy Brazilian population. ■ The prevalence of HPV16 in oropharyngeal squamous cell carcinoma was 10% in Brazilian samples. ■ The rate of HPV16 tonsillar infection should be lower than that reported previously in Brazil. ABSTRACT Objective: This study aimed to determine the prevalence of human papillomavirus (HPV) 16 infection in the tonsils of patients without cancer and to analyze the associated risk factors in a low-risk population in […]

Highlights ■ Evaluation of a corticosteroid-free antiemetic regimen. ■ Primary endpoint: 46% nausea control. ■ Secondary endpoint: 68% emesis control. ■ Comparable to standard four-drug protocols. ABSTRACT Objective: Chemotherapy-induced nausea and vomiting are highly prevalent adverse events that can lead to poor treatment adherence and a decreased quality of life. To the best of our knowledge, the complete omission of dexamethasone from any regimen for preventing nausea and vomiting has not yet been evaluated. This study aimed to evaluate the […]

Highlights ■ SARS-CoV-2 infection leads to mild-to-moderate disease in children with cystic fibrosis. ■ No worsening of cystic fibrosis was observed months after infection. ABSTRACT Objective: This study aimed to evaluate the clinical manifestations of SARS-CoV-2 in children and adolescents with cystic fibrosis. Methods: This was a case-control analysis of clinical variables and pulmonary function test results in 43 children with cystic fibrosis, 17 (39.5%) of whom tested positive for SARS-CoV-2. Results: The infected children exhibited a higher frequency of […]