02/May/2022
Evaluation of the prematurity retinopathy and other eye changes in the newborn
DOI: 10.31744/einstein_journal/2022AO6692
ABSTRACT Objective To assess the prevalence of ophthalmologic manifestations in newborns in a maternity hospital in the city of São Paulo, SP, and the main risk factors related with the development of retinopathy of prematurity. Methods A retrospective, longitudinal study with patients born from 2015 to 2017 who required ophthalmological evaluation. The research variables were obtained by analysis of the newborn medical charts. Results A total of 773 patients were studied. The sample consisted of 288 examinations performed by indication […]
Keywords: Infant, Newborn; Ophthalmology; Retinopathy of prematurity; Risk Factors
02/May/2022
Impacts of the COVID-19 pandemic on elective cataract surgeries
DOI: 10.31744/einstein_journal/2022AO6687
ABSTRACT Objective To evaluate the standards of practice of Brazilian cataract surgeons in relation to the protective measures adopted to mitigate the risks of transmission of COVID-19 during cataract surgery, in asymptomatic patients. Methods A descriptive, cross-sectional, quantitative paradigm study, developed from a self-administered electronic questionnaire sent to ophthalmologists and residents/specialists in ophthalmology in Brazil, who performed cataract surgeries in 2019 and 2020, connected through social media and mail listing from local societies. Results Of the 303 participating surgeons, 159 […]
Keywords: Cataract; Cataract extraction; Coronavirus infections; COVID-19; Phacoemulsification
28/Apr/2022
Matrix-assisted autologous chondrocyte transplantation for treatment of focal chondral lesions in the knee: the Hospital Israelita Albert Einstein experience
einstein (São Paulo). 28/Apr/2022;20:eAO6819.
View Article28/Apr/2022
Matrix-assisted autologous chondrocyte transplantation for treatment of focal chondral lesions in the knee: the Hospital Israelita Albert Einstein experience
DOI: 10.31744/einstein_journal/2022AO6819
ABSTRACT Objective Phase 1 clinical trial to determine feasibility, safety, and efficacy of a new advanced cell therapy product for treatment of knee articular cartilage injuries. Methods Three participants with knee focal chondral lesions were included, with no signs of osteoarthritis. Chondrocytes were obtained through knee arthroscopy, cultured in collagen membrane for 3 weeks at the laboratory, subjected to tests to release the cell therapy product, and implanted. All patients underwent a specific 3-month rehabilitation protocol, followed by assessments using […]
Keywords: Cartilage; Cell- and tissue-based therapy; Chondrocytes; Knee injuries; Pain; Regenerative medicine
28/Apr/2022
Eye diseases during pregnancy: a study with the medical data warehouse in the eye clinic of the Ludwig-Maximilians-Universität München in Munich in Germany
einstein (São Paulo). 28/Apr/2022;20:eAO6613.
View Article28/Apr/2022
Eye diseases during pregnancy: a study with the medical data warehouse in the eye clinic of the Ludwig-Maximilians-Universität München in Munich in Germany
DOI: 10.31744/einstein_journal/2022AO6613
ABSTRACT Objective To analyze the most common ophthalmologic disorders in pregnant women seen in a hospital in Munich in Germany using a big data analysis system, as well as to compare the results obtained with those from other epidemiological studies that used different data acquisition methods. Methods We retrospectively analyzed electronic health records of pregnant women who were seen at the ophthalmology department from 2003 to 2019 at the Ludwig-Maximilians-Universität München hospital. The main complaints that led to ophthalmic consultations […]
Keywords: Big data; Data warehousing; Eye diseases/complications; Pregnancy complications
28/Apr/2022
Body dissatisfaction among undergraduate medical students in the city of Juiz de Fora, Minas Gerais, Brazil
DOI: 10.31744/einstein_journal/2022AO6648
ABSTRACT Objective To assess the level of body dissatisfaction among undergraduate medical students in the city of Juiz de Fora, Minas Gerais, Brazil. Methods A cross-sectional study with 232 volunteers of both sexes at a private college. The Body Shape Questionnaire was used, which is a tool based on the sum of values that allow classifying body dissatisfaction according to the following scores: less than 111, if absence of body dissatisfaction; between 111 and 138, if mild body dissatisfaction; between […]
Keywords: Body image; Feeding and eating disorders; Mental Health; Nutritional status; Students, medical
28/Apr/2022
Post-varicella arterial ischemic stroke in children and neurocognitive performance: a 4-year follow-up study
DOI: 10.31744/einstein_journal/2022AO6360
ABSTRACT Objective To analyze data from children who were previously healthy and presented with post-varicella arterial ischemic stroke upon arrival when admitted to the emergency room, with focus on the clinical/laboratory aspects, and neurocognitive performance after four-year follow-up. Methods Seven children presenting with arterial ischemic stroke after varicella were evaluated at pediatric emergency services in the city of São Paulo (SP), Brazil. Ischemic stroke was determined by magnetic resonance imaging/magnetic resonance angiography in a topography compatible with the areas supplied […]
Keywords: Basal ganglia cerebrovascular disease; Chickenpox; Child; Stroke
28/Apr/2022
Evaluation of pulse wave velocity and central systolic blood pressure in children and adolescents with chronic kidney disease
einstein (São Paulo). 28/Apr/2022;20:eAO6758.
View Article28/Apr/2022
Evaluation of pulse wave velocity and central systolic blood pressure in children and adolescents with chronic kidney disease
DOI: 10.31744/einstein_journal/2022AO6758
ABSTRACT Objective Investigate pulse wave velocity and central systolic blood pressure among pediatric population with chronic kidney disease. Methods In this cross-sectional study, 57 patients (61.4% male) aged 6.2 to 17.5 years old, 44 with nondialysis chronic kidney disease and 13 on chronic dialysis, were included in the analysis. The pulse wave velocity and the central systolic blood pressure were measured with an oscillometric device with an inbuilt ARC SolverⓇ algorithm and were compared with previously established percentiles. Results The […]
Keywords: Adolescent; Arterial pressure; Cardiovascular diseases; Child; Pulse wave analysis; Renal insufficiency, chronic
25/Apr/2022
Real world evidence of the use of metamizole (dipyrone) by the Brazilian population. A retrospective cohort with over 380,000 patients
einstein (São Paulo). 25/Apr/2022;20:eAO6353.
View Article25/Apr/2022
Real world evidence of the use of metamizole (dipyrone) by the Brazilian population. A retrospective cohort with over 380,000 patients
DOI: 10.31744/einstein_journal/2022AO6353
ABSTRACT Objective To determine under which health conditions metamizole (dipyrone) is used as a single drug or as fixed-dose combination. Methods Two retrospective cohorts of Brazilian patients treated with metamizole between January 2015 and December 2017 were analyzed: a metamizole-based cohort (Cohort 1) and a symptoms-based cohort (Cohort 2). Anonymized patient data was obtained from Amil Clinical Data Warehouse. The number of patients with symptoms was described by age and sex. Results The sample size of the two cohorts consisted […]
Keywords: Antipyretics; Dipyrone; Drug combinations; Fever; Monotherapy; Pain
25/Apr/2022
C-reactive protein levels and prevalence of leukopenia in patients with inflammatory bowel disease treated with azathioprine and/or mesalazine: a real-life study
einstein (São Paulo). 25/Apr/2022;20:eAO6500.
View Article25/Apr/2022
C-reactive protein levels and prevalence of leukopenia in patients with inflammatory bowel disease treated with azathioprine and/or mesalazine: a real-life study
DOI: 10.31744/einstein_journal/2022AO6500
ABSTRACT Objective To examine serum C-reactive protein levels and the prevalence of leukopenia in patients with Crohn’s disease or ulcerative colitis undergoing treatment with azathioprine and/or mesalazine. Methods Retrospective observational study based on clinical and laboratory data collected from medical records of 76 adult patients with inflammatory bowel disease treated with azathioprine, mesalazine or both. Sex, age, diagnosis, number of blood samples and elevated serum C-reactive protein levels during the follow-up period were recorded. The following variables were analyzed in […]
Keywords: Azathioprine; C-reactive protein; Colitis, ulcerative; Crohn disease; Inflammatory bowel diseases; Leukopenia; Mesalamine; Proctocolitis
25/Apr/2022
Headache and rhinitis: pattern search on Google Trends for 17 years
einstein (São Paulo). 25/Apr/2022;20:eAO6224.
View Article25/Apr/2022
Headache and rhinitis: pattern search on Google Trends for 17 years
DOI: 10.31744/einstein_journal/2022AO6224
ABSTRACT Objective Headache and rhinitis are highly prevalent and comorbid. The objective of the present study is to analyze the correlation of headache and rhinitis, in addition to the temporal pattern of these diseases in 17 years, using the Google Trends platform. Methods Google Trends was searched from January 2004 to June 2021, using the entry: [“rinite” (rhinitis) + “dor de cabeça” (headache)” + “Alzheimer” + “enxaqueca” (migraine)]. Migraine, primary headache, and Alzheimer’s, with no clear relation with headache, were […]
Keywords: Alzheimer disease; Big data; Epidemiology; Headache; Migraine disorders; Rhinitis
