2 results

Sericin and swimming on histomorphometric parameters of denervated plantar muscle in Wistar rats

André Santana Junior, Jean Carlos Debastiani, Pâmela Buratti, Ana Luiza Peretti, Regina Inês Kunz, Rose Meire Costa Brancalhão, [...]

DOI: 10.1590/S1679-45082018AO4137

Abstract Objective To analyze the combined effects of the silk protein sericin and swimming exercise on histomorphometry of the plantar muscle in Wistar rats. Methods Forty adult rats were randomly allocated into 5 groups comprising 8 animals each, as follows: Control, Injury, Sericin, Swim, and Swim plus Sericin. Three days after crushing of the sciatic nerve the rats in the Swim and Swim plus Sericin Groups were submitted to swimming exercise for 21 days. Rats were then euthanized and the […]

Standardization of an experimental model suitable for studies on the effect of exercise on arthritis

Raquel Pinheiro Gomes, Elisangela Bressan, Tatiane Morgana da Silva, Monique da Silva Gevaerd, Carlos Rogério Tonussi, Susana Cristina Domenech

DOI: 10.1590/S1679-45082013000100014

Objective:To standardize an experimental model of chronic monoarthritis induced by complete Freund’s adjuvant appropriate for the analysis of the effect of walking on nociception and on joint edema.METHODS:The following factors were evaluated as to monoarthritis induction: route and site of administration, number and interval of inoculations, Mycobacterium species, and animal gender. Wistar male and female rats (200 to 250g) received two injections of complete Freund’s adjuvant containing Mycobacterium tuberculosis (1.0mg/mL; 50µL) or Mycobacterium butyricum (0.5mg/mL; 50µL) intra-articularly in the tibiotarsal […]