Highlights High fatigue and nutritional risk at discharge improved over one year in cancer survivors. Psychological symptoms, such as anxiety, depression, and posttraumatic stress disorder, remained prevalent for one year. 66% of patients had lasting symptoms or impairments after 12 months of follow-up. Nutritional risk was resolved in the following year. ABSTRACT Objective: Post-COVID symptoms are frequent and can be debilitating, particularly in individuals with cancer. However, their impact on this population remains unclear. This study aimed to prospectively assess […]

Highlights ■ SARS-CoV-2 infection leads to mild-to-moderate disease in children with cystic fibrosis. ■ No worsening of cystic fibrosis was observed months after infection. ABSTRACT Objective: This study aimed to evaluate the clinical manifestations of SARS-CoV-2 in children and adolescents with cystic fibrosis. Methods: This was a case-control analysis of clinical variables and pulmonary function test results in 43 children with cystic fibrosis, 17 (39.5%) of whom tested positive for SARS-CoV-2. Results: The infected children exhibited a higher frequency of […]

Highlights ■ Public intensive care unit COVID-19 patients presented with more comorbidities and higher severity at admission. ■ Public intensive care units required more invasive organ support (e.g., mechanical ventilation, vasopressors, and renal replacement therapy) but less non-invasive ventilation and high-flow nasal cannula than private intensive care units. ■ In-hospital mortality was higher in public intensive care units, with an increased risk of death even after adjusting for patient characteristics and illness severity at intensive care unit admission. ABSTRACT Objective: […]

Highlights ■ Probability of infection with a high SARS-CoV-2 viral load depends on mask-wearing habits. ■ The higher probability of infection with high viral load occurs for individuals that don’t use mask regularly [47.3%–79.8%]. ■ For individuals who use masks regularly, the probability is 38.6%–52.1%. ABSTRACT Objective: Previous studies indicated that face masks reduce the probability of infection by SARSCoV- 2 but did not examine the relationship between SARS-CoV-2 viral load and mask usage. This study analyzed this relationship. Methods: […]

Highlights Acute respiratory distress syndrome is a severe presentation of COVID-19 without effective treatment despite intensive research. Inhaled nitric oxide is a vasodilator that has been studied in patients with acute respiratory distress syndrome COVID-19 yielding contradictory results. The use of inhaled nitric oxide rescue therapy in critically ill patients with COVID-19 experiencing moderate-to-severe acute respiratory distress syndrome was significantly associated with an improvement in oxygenation parameters with no difference in mortality. ABSTRACT Objective: To evaluate the responsiveness of COVID-19 […]

Highlights Previous influenza vaccination was associated with a reduced need for hospitalization after COVID-19 diagnosis. In 60 days of outpatient setting, four deaths occurred (three in the hospitalized and one in the non-hospitalized group). The persistence of more than two symptoms in 60 days was observed in 31.9% of patients. ABSTRACT Objective: To evaluate deaths, hospitalizations, and persistence of symptoms in patients with COVID-19 after infection in an outpatient setting during the first COVID-19 wave in Brazil. Methods: This prospective […]

Highlights COVID-19 infection among healthcare personnel has impacted the workforce in hospitals. Knowledge of the risk factors for COVID-19 infection is important for disease prevention measures. Failure to train healthcare personnel is an important risk factor for acquiring COVID-19. ABSTRACT Objective: To verify the rate of COVID-19 infection among healthcare personnel at high and low risk of COVID-19 infection and identify the underlying risk factors. Methods: This crosssectional study was conducted between December 1, 2020 and February 28, 2021. Associations […]

Highlights Lung ultrasound enables precise diagnosis and ongoing monitoring of the disease. Ultrasound is an effective tool for assessing pulmonary findings in COVID-19. Structured reports enhance communication and are easily reproducible. ABSTRACT Objective: We aimed to share our experience in implementing a structured system for COVID-19 lung findings, elucidating key aspects of the lung ultrasound score to facilitate its standardized clinical use beyond the pandemic scenario. Methods: Using a scoring system to classify the extent of lung involvement, we retrospectively […]

Highlights Computed tomography revealed fibrotic-like lung changes in 10.9% of patients. Higher computed tomography scores were associated with a reduced DLCO (median computed tomography score, 6 versus 3; p=0.016). Fibrotic-like computed tomography changes were more prevalent in patients with DLCO impairment (p<0.001). Reduced DLCO had sensitivity and specificity of 73% and 88%, respectively, for predicting fibrotic-like computed tomography changes. ABSTRACT Objective: The radiological and functional lung sequelae in COVID-19 survivors remain unclear. We compared the chest computed tomography findings of […]

Highlights Face masks are associated with ear discomfort. Face masks increase the pulse rate. Face masks reduce arterial blood oxygen saturation. Face masks are less tolerated by young men. ABSTRACT Objective: The World Health Organization and Centers for Disease Control and Prevention recommend the use of face masks in public. This study aimed to evaluate the effects of face masks on pulse rate and partial blood oxygen saturation in patients without cardiorespiratory disorders. Methods: A total of 150 volunteers of […]