5 results
18/Nov/2024
18/Nov/2024
DOI: 10.31744/einstein_journal/2024AO0895
Highlights Psychostimulant use in the studied population revealed the following: ■ Lack of a valid diagnosis, unsupervised use, drug interactions, and adverse effects. ■ Concomitant use of alcohol and drugs and contraindications such as depression/anxiety. ■ Acquisition without prescription and use to improve academic performance. ABSTRACT Objective: To evaluate psychostimulant drug use among academics in the health area of a higher education institution in Minas Gerais, Brazil. Methods: We conducted an online cross-sectional study of 389 university students from various […]
Keywords: Academic performance; Central nervous system stimulants; Drug interactions; Health sciences; Illicit drugs; Learning; Performance-enhancing substances; Prescription drugs; Students; Universities
19/Aug/2019
19/Aug/2019
DOI: 10.31744/einstein_journal/2019AO4725
ABSTRACT Objective: To estimate the prevalence of drug interactions and associated factors among older adults followed up in a Comprehensive Medication Management Service at Primary Care. Methods: Firstly, the Beers criteria 2015 was used to define drug interactions; later, drug interactions proposed by Dumbreck for patients with diabetes, depression, and heart failure were evaluated. The associated factors were assessed by univariate (Pearson’s χ2) and multivariate analyses (logistic regression). The significance level of 5% was set for all analyses. Results: The […]
Keywords: Aged; Drug interactions; Medication therapy management; Pharmacists; Potentially inappropriate medication list
22/May/2019
DOI: 10.31744/einstein_journal/2019AO4521
ABSTRACT Objective: To characterize severe potential drug interactions in maternal intensive care, and to determine their frequency, risk factors and potential risk medications. Methods: An observational and longitudinal study conducted between December 2014 and December 2015 in a maternal intensive care unit. Clinical data were collected and severe potential drug interactions were identified on pregnant inpatients. The drug interactions were classified by type, prevalence and exposure rate. A multivariate logistic regression model was used to identify the severe potential drug […]
Keywords: Drug interactions; Drug therapy; Intensive care units; Maternal health; Pregnancy
31/Jan/2014
DOI: 10.1590/S1679-45082013000400010
OBJECTIVE: To identify the occurrence of potential drug interactions in prescriptions for adult patients admitted to the Emergency Department of Hospital São Paulo. METHODS: A cross-sectional and descriptive study. Its sample consisted of 200 medical prescriptions. The analysis of drug interactions was performed using the Drugs.com database, where they are classified according to severity of interaction as severe, moderate, mild and without interaction. RESULTS: The number of drugs in prescriptions ranged from 2 to 19, and the average per prescription […]
Keywords: Drug interactions; Drugs incompatibility; Patient safety
19/Sep/2012
DOI: 10.1590/S1679-45082012000100024
Oral anticoagulants are among the drugs with the greatest number of drug interactions. The concomitant use of several medications is a common practice in patients with cardiovascular problems, who often also present with depression; therefore, the probability of an interaction occurring between warfarin and the antidepressants is high, and may result in increased or decreased anticoagulant activity. Since the possible interactions between these two classes of drugs have been poorly explored in literature, with a risk to the patients who […]
Keywords: Anticoagulants; Antidepressive agents; Drug interactions; Warfarin