4 results
08/Aug/2025
DOI: 10.31744/einstein_journal/2025AO1437
Highlights ■ This prospective cohort study assessed prostate biopsy complications in 1,043 men. ■ The major outcomes included bleeding (Clavien-Dindo Grades 2–3 = 1.5%), infections (4.7%), and urinary retention (4.1%). ■ The key risk factors for infection were recent quinolone use, indwelling catheters, and high PSA levels. ■ Acute urinary retention was linked to untreated lower urinary tract symptoms, prostate volume, intravesical prostatic protrusion, and bladder wall thickness. ABSTRACT Objective: To identify complications following transrectal posterior biopsies in a public […]
Keywords: Drug resistance; Early detection of cancer; Image-guided biopsy; Mass screening; Prostatic diseases; Risk Factors; Urinary tract infections
06/Nov/2024
DOI: 10.31744/einstein_journal/2024RW0611
ABSTRACT Objective: MicroRNAs are small non-coding RNAs that are abundantly expressed in various biofluids, making them promising candidates for cancer biomarkers. This review aims to present current evidence on the use of miRNA as biomarkers for the non-invasive diagnosis of bladder cancer. Methods: A systematic literature review, using the Medline database, was performed in July 2022 according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. All articles were required to satisfy the risk-of-bias assessment using the Joanna […]
Keywords: Early detection of cancer; Niomarkers; Urinary bladder neoplasms
06/Aug/2024
DOI: 10.31744/einstein_journal/2024AO0771
Highlights Multicancer early detection panels are novel assays that allow screening for dozens of cancers using a single blood sample. Data on the optimal workflow for ordering, interpreting, and managing subsequent evaluations of multi-cancer early detection results are lacking. Primary care providers expressed concerns about the cost and management of subsequent evaluations for a positive multicancer early detection test. ABSTRACT Objective Multicancer early detection panels have recently become available to patients with healthcare provider prescriptions and available funds. These tests […]
Keywords: Delivery of health care; Early detection of cancer; Health equity; High-value care; Primary Health Care; Quality of Health Care; Surveys and questionnaires
15/Dec/2021
DOI: 10.31744/einstein_journal/2021AO6721
ABSTRACT Objective To evaluate the impact of COVID-19 pandemic on breast cancer diagnosis in a breast imaging center. Methods This was a retrospective cohort study that included women submitted to breast exams and procedures in a private hospital in São Paulo, SP, Brazil, as from the period of most strict social isolation measures, in 2020 (separated in first period of social isolation, March 24 to June 21, 2020, and second period, June 22 to December 31, 2020), as compared to […]
Keywords: Brazil; Breast cancer screening; Breast neoplasms; Coronavirus infections; Early detection of cancer; Magnetic resonance spectroscopy; Mammography; Prognosis; Ultrasonography, mammary