Highlights ■ Typical perifissural nodules remain radiologically stable with no metastatic potential. ■ Only two nodules progressed to metastasis (one atypical perifissural nodule and one non-perifissural nodule). ■ Atypical and non-perifissural nodules require closer follow-up. ■ Annual growth rate was a strong marker of malignancy. ABSTRACT Objective: To evaluate whether pulmonary nodules adjacent to fissures, particularly perifissural nodules detected on chest computed tomography in patients with hepatocellular carcinoma, can be reliably classified as benign based on their radiological characteristics. Methods: […]

Highlights ■ Higher absorbed doses are associated with positive tumor responses in patients with hepatocellular carcinoma treated with Y-90 radioembolization. ■ Personalized dosimetry may improve treatment outcomes in selected patients. ■ Dosimetric parameters such as D30, D50, and D70 also correlate positively with objective responses, emphasizing the importance of precise dose calculation in treatment planning. ABSTRACT Objective: To evaluate the relationship between the absorbed dose and radiological response in patients with hepatocellular carcinoma undergoing resin microsphere radioembolization to enhance treatment […]

Highlights Once complete hepatocellular carcinoma necrosis is achieved, the diameter of the hepatocellular carcinoma decreases significantly, regardless of its initial size. Hepatocellular carcinoma >3cm showed greater reduction and longer time to recurrence. Hepatocellular carcinoma ≤3cm exhibited a shorter time to relapse. Recurrence rates were similar, as long as complete response was achieved. ABSTRACT Objective: To describe the radiological characteristics of hepatocellular carcinoma (HCC) lesions that achieved a complete response following drug-eluting bead transarterial chemoembolization (DEB-TACE) preceding liver transplantation. Methods: This […]

OBJECTIVES: To evaluate the efficacy of microbubble contrast ultrasound in diagnosis of hepatocellular carcinoma and to compare its results with those of magnetic resonance and histopathology. METHODS: A total of 29 patients suffering from chronic liver diseases and awaiting liver transplants at Hospital Israelita Albert Einstein were subject to magnetic resonance, microbubble contrast ultrasound, and excision liver biopsies. RESULTS: Excellent agreement between magnetic resonance and microbubble contrast ultrasound was observed in this study. There was moderate agreement between both imaging […]