einstein (São Paulo). 01/Apr/2011;9(2 Pt 1):119-23.
Autologous stem-cell transplantation for multiple myeloma: a Brazilian institution experience in 15 years of follow-up
DOI: 10.1590/S1679-45082011AO1845
ABSTRACT
Objective:
To determine the 5-year post-transplant survival of patients with multiple myeloma.
Methods:
A retrospective study in patients diagnosed with multiple myeloma submitted to autologous bone marrow transplantation at a Brazilian institution, during the period of 1993 to 2007.
Results:
Seventy-three patients were evaluated with a median age of 55 years. Survival in 5 years was 75% (2.4 to 60 months). Statistical analysis demonstrated statistical significance for the applied grade of response prior to treatment with autologous bone marrow transplantation (p = 0.01). There was no statistical significance for clinical staging or time of diagnosis (before or after the year 2000).
Conclusion:
Experience in autologous bone marrow transplantation for multiple myeloma at a Brazilian institution demonstrated an evolution consistent with that of medical literature and highlighted the importance of a response to treatment prior to transplantation in the survival of these patients.
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