einstein (São Paulo). 01/Mar/2014;12(1):42-7.

Analysis of oxybutynin treatment for hyperhidrosis in patients aged over 40 years

Nelson Wolosker, Mariana Krutman, Marcelo Passos Teivelis, Rafael Pessanha de Paula, Paulo Kauffman, Jose Ribas Milanez de Campos, Pedro Puech-Leão

DOI: 10.1590/S1679-45082014AO2841

Our aim was to analyze the effectiveness of oxybutynin for hyperhidrosis treatment in patients over 40 years.
: Eighty-seven patients aged over 40 years were divided into two groups. One group consisted of 48 (55.2%) patients aged between 40 and 49 years, and another was composed of 39 (44.8%) patients aged over 50 years (50 to 74 years). A comparative analysis of Quality of Life and level of hyperhidrosis between the groups was carried out 6 weeks after a protocol treatment with oxybutynin. A validated clinical questionnaire was used for evaluation.
: In the younger age group, 75% of patients referred a “partial” or “great” improvement in level of hyperhidrosis after treatment. This number was particularly impressive in patients over 50 years, in which 87.2% of the cases demonstrated similar levels of improvement. Over 77% of patients in both groups demonstrated improvement in Quality of Life. Excellent outcomes were observed in older patients, in which 87.1% of patients presented “slightly better” (41%) or “much better” (46.1%) improvement.
: Patients aged over 40 years with hyperhidrosis presented excellent results after oxybutynin treatment. These outcomes were particularly impressive in the age group over 50 years, in which most patients had significant improvement in Quality of Life and in level of hyperhidrosis.

Analysis of oxybutynin treatment for hyperhidrosis in patients aged over 40 years