Highlights ■ Calf circumference is a well-established indicator of all-cause mortality. ■ In women with peripheral artery disease, calf circumference was inversely associated with arterial stiffness. ■ Among men with peripheral artery disease, calf circumference was not associated with cardiovascular indicators. ■ Calf circumference may be a useful screening tool for cardiovascular risk in women. ABSTRACT Objective: To analyze the association between calf circumference and cardiovascular indicators in men and women with symptomatic peripheral artery disease. Methods: This cross-sectional study […]

Highlights ■ Two gene groups with contrasting expression profiles were identified. ■ The ATP1B3 and SLCOB3 gene profiles classified patients with 90% accuracy. ■ The ATP1B3 and SLCOB3 gene signature is a potential predictor of treatment response. ABSTRACT Introduction: Cervical cancer is the fourth most common cancer in women worldwide. Resistance to chemoradiotherapy in cervical cancer has been widely associated with membrane transport-related genes, particularly those encoding efflux transport proteins, such as the ATP-binding cassette family members (including P-glycoprotein), which […]

Highlights ■ Matching methodologies may reduce bias in economic evaluations. ■ Liver transplantation within the Proadi-SUS context has an incremental cost-effectiveness ratio below the Health Technology Incorporation in the Brazilian Health System threshold. ■ The patients who received transplant had a median survival of 10.1 years after list enrollment. ■ The mean cost per transplanted patient was US$ PPP 162,821.96. ABSTRACT Objective: To estimate the incremental cost and survival of patients on the liver transplantation waiting list who were referred […]

Highlights ■ A 13-week Tai Chi/Qigong program significantly reducedanxiety and stress in Brazilian patients with diabetes and hypertension. ■ Tai Chi/Qigong offers an effective complementary therapy to improve health outcomes in primary care settings. ■ This study highlights the potential of Tai Chi/Qigong for enhancing mental and physical well-being in chronic disease management. ABSTRACT Objective: This study investigated the effects of Tai Chi/Qigong practice over 13 weeks on anxiety and perceived stress levels in middle-aged or older Brazilian hypertensive and […]

Highlights ■ Imaging plays a fundamental role in the diagnosis of acute appendicitis. ■ The study highlights ultrasound’s effectiveness in diagnosing appendicitis. ■ APPENDIC-RADS efficiently standardizes the ultrasound evaluation of appendicitis. ■ Using APPENDIC-RADS may enhance communication and optimize medical practices. ABSTRACT Objective: Abdominal ultrasonography is widely used to evaluate suspected cases of appendicitis. Objective descriptions of the direct and indirect signs of appendicitis result in varied assessments of its likelihood. This study introduces the Appendix Imaging Reporting and Data […]