2 results

Analysis of cytokine profile and growth factors in platelet-rich plasma obtained by open systems and commercial columns

Alberto de Castro Pochini, Eliane Antonioli, Daniella Zanetti Bucci, Luiz Roberto Sardinha, Carlos Vicente Andreoli, Mario Ferretti, [...]

DOI: 10.1590/S1679-45082016AO3548

ABSTRACTObjective:To evaluate growth factors and cytokines in samples of platelet-rich plasma obtained by three different centrifugation methods.Methods:Peripheral blood of six individuals with no hematological diseases, aged 18 to 68 years, was drawn to obtain platelet-rich plasma, using the open method and commercial columns by Medtronic and Biomet. The products obtained with the different types of centrifugation were submitted to laboratory analysis, including pro-inflammatory cytokines and chemokines by flow cytometry assays, the concentration of fibroblast growth factors-2 (FGF-2) and transforming growth […]

Platelet-rich plasma for long bone healing

Mário Lenza, Silvia de Barros Ferraz, Dan Carai Maia Viola, Oscar Fernando Pavão dos Santos, Miguel Cendoroglo Neto, Mario Ferretti

DOI: 10.1590/S1679-45082013000100023

Objective:To evaluate effectiveness of the use of platelet-rich plasma as coadjuvant for union of long bones.METHODS:The search strategy included the Cochrane Library (via Central) and MEDLINE (via PubMed). There were no limits as to language or publication media. The latest search strategy was conducted in December 2011. It included randomized clinical trials that evaluated the use of platelet-rich plasma as coadjuvant medication to accelerate union of long bones (acute fractures, pseudoarthrosis and bone defects). The outcomes of interest for this […]