3 results
26/Nov/2024
26/Nov/2024
DOI: 10.31744/einstein_journal/2024AO0563
Highlights ■ Convalescent plasma did not affect the outcomes. ■ Convalescent plasma improved some laboratory parameters but had no impact on clinical outcomes. ■ Dialysis and the World Health Organization severity score on day 0 influenced the outcomes. ABSTRACT Objective: This study compared the outcomes of two cohorts of patients with coronavirus disease 2019 (COVID-19) who received COVID-19 convalescent plasma transfusions between 2020 and 2021. Methods: This retrospective study was conducted at a tertiary hospital in São Paulo, Brazil. We […]
Keywords: COVID-19 serotherapy; Dialysis; Hospitalization; Immunization, passive; Inflammation; Plasma
02/Feb/2022
DOI: 10.31744/einstein_journal/2022RC6550
ABSTRACT The coronavirus disease 19 (COVID-19) is responsible for the current worldwide pandemic. Treatment and prophylaxis are still under investigation. Convalescent plasma therapy could be an alternative. We report a case of a 41-year-old patient, at 28 weeks of gestation, was hospitalized with COVID-19. On the 10th day after onset of symptoms, the clinical picture worsened, and she required high-flow oxygen therapy (30L/minute), with 92% oxygen saturation, and chest X-ray showing mild bilateral opacities at lung bases. Blood tests showed […]
Keywords: Antibodies, neutralizing; Convalescent plasma; Coronavirus infections; COVID-19; Plasma; Pregnancy; Pregnancy complications, infectious
09/Apr/2021
09/Apr/2021
DOI: 10.31744/einstein_journal/2021RW6186
ABSTRACT The objective of this study was to highlight the global scientific effort to fight the SARS-CoV-2, addressing the preliminary results of passive immunization through convalescent plasma. We performed a search at the major databases of interventional clinical trial protocols about the transfusion of convalescent plasma in patients with COVID-19, as well as, published articles (n≥25), using the following search strategy: [(COVID-19 OR SARS-CoV-2 OR nCoV-2019) AND (Convalescent plasma OR Plasma exchange) AND (Treatment OR Therapy)]. A total of 24 […]
Keywords: Betacoronavirus; Convalescent plasma; Coronavirus infections; COVID-19; Immunization; Immunization, passive; Plasma; SARS-CoV-2