3 results
28/Apr/2025
DOI: 10.31744/einstein_journal/2025AO1124
Highlights ■ Evaluation of a corticosteroid-free antiemetic regimen. ■ Primary endpoint: 46% nausea control. ■ Secondary endpoint: 68% emesis control. ■ Comparable to standard four-drug protocols. ABSTRACT Objective: Chemotherapy-induced nausea and vomiting are highly prevalent adverse events that can lead to poor treatment adherence and a decreased quality of life. To the best of our knowledge, the complete omission of dexamethasone from any regimen for preventing nausea and vomiting has not yet been evaluated. This study aimed to evaluate the […]
Keywords: Antineoplastic agents; Breast neoplasms; Dexamethasone; Drug therapy; Drug-related side effects and adverse reactions; Nausea; Olanzapine; Vomiting
31/Oct/2024
31/Oct/2024
DOI: 10.31744/einstein_journal/2024AO0849
Highlights ■ Mechanical ventilation and mortality rates remained stable. ■ The birth rate at <28 weeks’ gestation increased during the evaluation period. ■ The overall rate of dexamethasone administration was low; however, its use was more significant in infants aged <28 weeks. ABSTRACT Objective: To evaluate temporal trends in the use of dexamethasone for the treatment of bronchopulmonary dysplasia in very-low-birth-weight preterm infants. Methods: A cohort study was conducted using an electronic database and medical records of all very low-birth-weight […]
Keywords: Bronchopulmonary dysplasia; Dexamethasone; Infant, premature; Infant, very low birth weight; Trends
20/Oct/2021
DOI: 10.31744/einstein_journal/2021AO6177
ABSTRACT Objective The aim of this study was to evaluate patients with complete response of oral chronic graft-versus-host disease to immunosuppressive treatment. Methods A total of 29 patients submitted to allogeneic hematopoietic stem cell transplantation, with oral chronic graft-versus-host disease, were enrolled in this retrospective study, from September 2012 to February 2018. Patients were treated with combined topical dexamethasone solution and topical tacrolimus ointment, combined topical dexamethasone and topical tacrolimus, systemic immunosuppressive medication, and topical dexamethasone only. Results The mean […]
Keywords: Bone morrow transplantation; Dexamethasone; Graft vs host disease; Hematopoietic stem cell transplantation; Tacrolimus