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Urethral tumors are rare and aggressive. They usually affect men (2:1) and occur more commonly in white (85% of cases). Soft tissue sarcomas are a heterogeneous group of tumors that arise from embryonic mesoderm. It represents 1% of all cases of urinary tract malignancies and rarely primary affect the ureter. We report a case of male urethral sarcoma. To date, only two similar cases have been published in literature.
Male urethral sarcoma: a case report and literature review
NogueiraMA, SantosGCL, LopesRI, CamposOHA, Dall'OglioMF, Sant'AnnaAC. Male urethral sarcoma: a case report and literature review. Einstein (Sao Paulo). 2015;14(1):64-6. https://doi.org/10.1590/S1679-45082015RC2992
Nogueira,Magno Almeida; Santos,Guilherme Campelo Lopes dos; Lopes,Roberto Iglesias; Campos,Octavio Henrique Arcos; Dall'Oglio,Marcos Francisco; Sant'Anna,Alexandre Crippa. Male urethral sarcoma: a case report and literature review. Einstein (Sao Paulo)., v. 14, n. 1, p. 64-66, Sep. 2015. https://doi.org/10.1590/S1679-45082015RC2992
Nogueira,M.A., Santos,G.C.L. , Lopes,R.I., Campos,O.H.A., Dall'Oglio,M.F., & Sant'Anna,A.C. (2015). Male urethral sarcoma: a case report and literature review. Einstein (Sao Paulo).,14(1), 64-66. https://doi.org/10.1590/S1679-45082015RC2992
Nogueira,Magno Almeida and Santos,Guilherme Campelo Lopes dos and Lopes,Roberto Iglesias and Campos,Octavio Henrique Arcos and Dall'Oglio,Marcos Francisco and Sant'Anna,Alexandre Crippa. Male urethral sarcoma: a case report and literature review. Einstein (Sao Paulo). [online]. 2015, vol. 14, n. 1, [cited 2025-09-27], pp.64-66. Available from: <https://journal.einstein.br/article/male-urethral-sarcoma-a-case-report-and-literature-review/>. ISSN 1679-4508. https://doi.org/10.1590/S1679-45082015RC2992
Figure 3
(A) High degree urethral sarcoma; (B) Immunohistochemical analysis that revealed strong positivity of vimentin; (C) Urethral tumor also showing positivity for desmin
(A) High degree urethral sarcoma; (B) Immunohistochemical analysis that revealed strong positivity of vimentin; (C) Urethral tumor also showing positivity for desmin