ABSTRACT Objective To evaluate quality of life and associated factors in patients with leprosy. Methods A cross-sectional study with 63 people diagnosed as leprosy, seen at a reference service for the disease in the southeastern region of Mato Grosso, Brazil. The questionnaire World Health Organization Quality of Life Bref was used to evaluate quality of life. Simple and multiple linear regressions evaluated the association between sociodemographic variables and quality of life domains. Results The highest mean of quality of life […]

ABSTRACT Objective To compare the effectiveness of oral progestins and injectable gonadotropin-releasing hormone antagonist medication in cancer fertility preservation in patients with breast cancer. Methods A cross-sectional study with 40 breast cancer patients submitted to cancer fertility preservation, who were divided into two groups according to histochemical analysis of progesterone receptors to define luteinizing hormone block: if positive, use of gonadotropin-releasing hormone antagonist, if negative, use of oral progestins. The mean age, medication days, antral follicle count, number of oocytes […]

ABSTRACT Objective To analyze the impact of COVID-19 on emergency department metrics at a large tertiary reference hospital in Brazil. Methods A retrospective analysis of consecutive emergency department visits, from January 1, 2020, to November 21, 2020, was performed and compared to the corresponding time frame in 2018 and 2019. The volume of visits and patients’ demographic and clinic characteristics were compared. All medical conditions were included, except confirmed cases of COVID-19. Results A total of 138,138 emergency department visits […]

ABSTRACT Objective To evaluate the morphology and morphometry of the muscles extensor digitorium longus and soleus of C57BL/6 females, who were exposed to glyphosate during pregnancy and lactation. Methods Twelve female mice from the C57BL/6 lineage were used. After detection of pregnancy, they were divided into a Control Group, which received only water, and a Glyphosate Group, which received water with 0.5% glyphosate during pregnancy and lactation. Both groups received ad libitum standard diet. After weaning, the females were euthanized […]

ABSTRACT Objective To determine the impact of risk factors on infant mortality in the Metropolitan Region of São Paulo according to maternal and neonate characteristics, as well as mode of delivery. Methods An ecological, quantitative study based on secondary data retrieved from infant mortality and live birth data systems. Data from 39 municipalities located in the Metropolitan Region of São Paulo were analyzed. Newborn and maternal variables were extracted from the Information Technology Department of the Unified Health System. Absolute […]

ABSTRACT Objective: To compare the traditional printed form of the Behavioral Regulation in Exercise Questionnaire with a proposed online form in terms of validity, reliability, and applicability. Methods: A crossover design study was conducted with 157 undergraduate students. Half of the sample answered the printed questionnaire first and then answered the online questionnaire 7 days later, while the other half of the sample did the inverse. Cronbach’s alpha was used to analyze the internal consistency of both the online and […]

ABSTRACT Objective To examine the association of between serum fibroblast growth factor 23 and the functional capacity among independent individuals, aged 80 or older. Methods The functional capacity of 144 elderly was assessed by Instrumental Activities of Daily Living, cognitive tests, handgrip strength and the timed ability to rise from a chair and sit down five times. Fibroblast growth factor 23 was measured using an ELISA assay. Results Participants in the lowest fibroblast growth factor 23 tertile had the highest […]

ABSTRACT Objective To assess Google Trends accuracy for epidemiological surveillance of dengue and yellow fever, and to compare the incidence of these diseases with the popularity of its terms in the state of São Paulo. Methods Retrospective cohort. Google Trends survey results were compared to the actual incidence of diseases, obtained from Centro de Vigilância Epidemiológica “Prof. Alexandre Vranjac”, in São Paulo, Brazil, in periods between 2017 and 2019. The correlation was calculated by Pearson’s coefficient and cross-correlation function. The […]

ABSTRACT Objective To evaluate the prevalence and factors associated with non-vaccination against influenza in the risk group. Methods A cross-sectional, population-based study, carried out in the city of Rio Grande (RS). The outcome was defined as belonging to risk groups and not having been vaccinated in the last 12 months. Demographic, socioeconomic, behavioral variables, and access for health services were analyzed. Results In this study, 680 individuals participated. The prevalence was 46.0% (95%CI: 41.8-50.3), ranging from 27.9% (elderly) to 81.8% […]

ABSTRACT Objective Humidity and temperature are fundamental for the balance in the life cycle of living beings and, consequently, for maintaining the well-being of the human population and reducing the prevalence of infectious diseases. Thus, in order to mitigate the impact of climate change, especially in the period when humidity is not the ideal, it is necessary to adopt some assistance measures. The present experimental study aims to elucidate what would be the recommended option to improve the quality of […]