Highlights This study focused on a prenatal biocellulose-based repair technique for open spina bifida that was performed at a later gestational age (26–28 weeks). Myelomeningocele repair involves placode and myofascial flap dissections, with the placement of a biocellulose patch that contributes to successful outcomes, by inducing the formation of a neodurameter. Only 4.4% of patients required cord untethering, indicating a notably low rate of tethered cord syndrome associated with the procedure, especially when compared with other prenatal myelomeningocele-correction techniques. The […]