28/Mar/2025
Neuron-specific enolase and Tau protein as biomarkers for sepsis-associated delirium: a cross-sectional pilot study
einstein (São Paulo). 28/Mar/2025;23:eAO1244.
View Article28/Mar/2025
Neuron-specific enolase and Tau protein as biomarkers for sepsis-associated delirium: a cross-sectional pilot study
DOI: 10.31744/einstein_journal/2025AO1244
Highlights ■ Biomarkers of brain injury, such as neuron-specific enolase and Tau proteins, are higher in older patients with sepsis and delirium. ■ Diagnosing sepsis in patients with delirium can be challenging. ■ Early identification of sepsis is key to managing sepsisassociated delirium. ABSTRACT Objective: Sepsis-associated delirium is a common cerebral manifestation in patients with sepsis, potentially caused by a combination of neuroinflammation and other neurophysiological disorders. This study investigated the expression of neuron-specific enolase and Tau protein as biomarkers […]
Keywords: Biomarkers; Delirium; Emergency medicine; Neuroinflammatory diseases; Sepsis
26/Nov/2024
APENDIC-RADS: an ultrasound reporting system for the diagnosis of acute appendicitis
DOI: 10.31744/einstein_journal/2024AO1164
Highlights ■ Imaging plays a fundamental role in the diagnosis of acute appendicitis. ■ The study highlights ultrasound’s effectiveness in diagnosing appendicitis. ■ APPENDIC-RADS efficiently standardizes the ultrasound evaluation of appendicitis. ■ Using APPENDIC-RADS may enhance communication and optimize medical practices. ABSTRACT Objective: Abdominal ultrasonography is widely used to evaluate suspected cases of appendicitis. Objective descriptions of the direct and indirect signs of appendicitis result in varied assessments of its likelihood. This study introduces the Appendix Imaging Reporting and Data […]
Keywords: Appendicitis; Emergency medicine; Interdisciplinary communication; Ultrasonography
23/May/2023
Epipericardial fat necrosis as a differential diagnosis of acute chest pain: a case report and algorithm proposal for diagnostic approach
einstein (São Paulo). 23/May/2023;21:eRC0183.
View Article23/May/2023
Epipericardial fat necrosis as a differential diagnosis of acute chest pain: a case report and algorithm proposal for diagnostic approach
DOI: 10.31744/einstein_journal/2023RC0183
ABSTRACT Chest pain is a frequent, potentially life-threatening condition in the emergency department and requires immediate investigation and treatment. This case report highlights a rare differential diagnosis of pleuritic chest pain: epipericardial fat necrosis. A 29-year-old man presented with normal clinical evaluation, electrocardiography, point-of-care ultrasound, and unremarkable laboratory tests. The initial hypothesis was acute pleuritis. Chest radiography revealed peri-cardiac nonspecific findings, and computed tomography revealed epicardial fat necrosis. Despite the rarity of this condition, accurate diagnosis allows for better practices. […]
Keywords: Algorithms; Chest pain; Emergency medicine; Fat necrosis; Pericardium
01/Feb/2019
Assessing how emergency and trauma ultrasonography is taught to medical students
DOI: 10.31744/einstein_journal/2019AO4469
ABSTRACT Objective To evaluate a method aimed at teaching ultrasound techniques to medical students in emergency settings. Methods A prospective study conducted with 66 sixth-year undergraduate medical students. Students participated in theory and practicing sessions with a 5-hour load; knowledge acquisition was assessed through pre- and post-course and 90-day tests. A questionnaire were distributed to the students after course completion for theoretical and practical knowledge assessment. Results Average pre-test grade in theoretical content evaluation was 4.9, compared to 7.6 right […]
Keywords: Educational measurement; Emergency medicine; Multiple trauma; Teaching; Ultrasonography