einstein (São Paulo). 03/Feb/2026;24:eRC2002.

Thyroid cartilage resection surgery for metastases of clear cell renal cell carcinoma: case report and literature review

Lorenzo Zanardo , Gustavo Barreto da , Maria Luísa Pedalino , Leonardo , Fabio Pupo

DOI: 10.31744/einstein_journal/2026RC2002

ABSTRACT

Laryngeal cartilage is an exceptionally rare site of metastasis, with fewer than 63 cases reported in the literature; prostate, kidney, breast, and lung cancers are the most common primary tumors. In addition to this extreme rarity, most published reports are limited to descriptions of the lesion and radiologic findings, without detailing management strategies or follow-up outcomes. The limited number of studies exploring surgical intervention have primarily described superficial resections or conventional laryngectomies. In this context, this case report describes thyroid cartilage metastasis of clear cell renal cell carcinoma in an asymptomatic patient, treated with an innovative surgical approach based on isolated thyroid cartilage resection, with a nine-year follow-up.

Thyroid cartilage resection surgery for metastases of clear cell renal cell carcinoma: case report and literature review
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