einstein (São Paulo). 21/Aug/2020;18:eRW5160.
The role of adiponectin in ischemia-reperfusion syndrome: a literature review
DOI: 10.31744/einstein_journal/2020RW5160
ABSTRACT
Adiponectin, among other diverse adipokines, is produced in greater quantity and has an effect on the adipose tissue and other tissues in the body. Adiponectin plays three main roles: regulatory metabolic and sensitizing function of insulin in the liver and muscles; it acts as an anti-inflammatory cytokine and in vascular protection, besides important cardiac protection in the presence of ischemia-reperfusion syndrome. Since many situations resulting from traumatic accidents or pathologies are due to cell damage caused by ischemia-reperfusion syndrome, it is relevant to study new therapeutic alternatives that will contribute to reducing these lesions. The objective of this study is to carry out a literature review on the role of adiponectin in ischemia-reperfusion syndrome.
Keywords: Adiponectin; Ischemia; Reperfusion injury
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