The journal einstein (São Paulo) – e-ISSN 2317-6385 is dedicated to dissemination of high-quality scientific content that advances our understanding of human disease with the goal of improving prevention, care, diagnostics and treatment of patients globally.
The incidence of inflammatory bowel disease in the pediatric population has increased in the last years. The most common form of inflammatory bowel disease is Crohn’s disease and, according to its form and age of presentation, it is possible to predict the evolution of the disease.
Specificities of presentation of Crohn’s disease in childhood
ProtásioBKPF, BarbosaCMPMM, NeufeldCB, BuckLD, LaundLSL, ToporovskiMS, VisoniTC. Specificities of presentation of Crohn’s disease in childhood. Einstein (São Paulo) 2018;16(1):eRC4070. https://doi.org/10.1590/S1679-45082017RC4070
Protásio,Bruna Karoline Pinheiro França; Barbosa,Camila Maria Pinheiro Machado Martins; Neufeld,Clarice Blaj; Buck,Leandro Dimasi; Laund,Lygia de Souza Lima; Toporovski,Mauro Sergio; Visoni,Thais Cristina. Specificities of presentation of Crohn’s disease in childhood. Einstein (São Paulo), v. 16, n. 1, eRC4070, Apr. 2018. https://doi.org/10.1590/S1679-45082017RC4070
Protásio,B.K.P.F., Barbosa,C.M.P.M.M., Neufeld,C.B., Buck,L.D., Laund,L.S.L., Toporovski,M.S., & Visoni,T.C. (2018). Specificities of presentation of Crohn’s disease in childhood. Einstein (São Paulo),16(1), eRC4070. https://doi.org/10.1590/S1679-45082017RC4070
Protásio,Bruna Karoline Pinheiro França and Barbosa,Camila Maria Pinheiro Machado Martins and Neufeld,Clarice Blaj and Buck,Leandro Dimasi and Laund,Lygia de Souza Lima and Toporovski,Mauro Sergio and Visoni,Thais Cristina. Specificities of presentation of Crohn’s disease in childhood. Einstein (São Paulo) [online]. 2018, vol. 16, n. 1, [cited 2026-02-03], eRC4070. Available from: <https://journal.einstein.br/article/specificities-of-presentation-of-crohns-disease-in-childhood/>. ISSN 1679-4508. https://doi.org/10.1590/S1679-45082017RC4070
Figure 1
Somatic mutation rates tend to be lower in hematological malignancies. (A) Total numbers of mutations for each tumor in the Pan-Cancer Analysis of Whole Genomes, grouped by tissue type. Hematological tumors are indicated with red arrow. (B) Same as panel (A), but here, tumors are grouped by specific cancer type. Red arrows indicate hematological cancers. Note that all hematological cancers are among the less frequently mutated types, save B-cell non-Hodgkin lymphoma (BNHL)
