einstein (São Paulo). 01/Oct/2016;14(4):580-4.
Sarcopenia and chemotherapy-mediated toxicity
DOI: 10.1590/S1679-45082016MD3740
ABSTRACT
This narrative review focuses on the role of sarcopenia and chemotherapy-induced toxicity in cancer patients. Consistent evidence shows that sarcopenia in cancer patients leads to decreased overall survival by influencing treatment discontinuation and dose reduction. Therefore, sarcopenia should be considered a robust prognostic factor of negative outcome as well as a determinant of increased healthcare costs.
Sarcopenia and chemotherapy-mediated toxicity
Keywords: Sarcopenia/drug therapy; Muscles/pathology; Neoplasms; Inflammation
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