einstein (São Paulo). 19/May/2015;13(2):202-8.
Relation between uric acid and metabolic syndrome in subjects with cardiometabolic risk
DOI: 10.1590/S1679-45082015AO3194
Objective
To identify possible relations between serum uric acid levels and metabolic syndrome and its components in a population with cardiometabolic risk.
Methods
This cross-sectional study included 80 subjects (46 women), with mean age of 48±16 years, seen at the Cardiovascular Health Program.
Results
The prevalence of hyperuricemia and metabolic syndrome was 6.3% and 47.1%, respectively. Uric acid level was significantly higher in individuals with metabolic syndrome (5.1±1.6mg/dL), as compared to those with no syndrome or with pre-syndrome (3.9±1.2 and 4.1±1.3mg/dL, respectively; p<0.05). The uric acid levels were significantly higher in men presenting abdominal obesity, and among women with abdominal obesity, lower HDL-c levels and higher blood pressure (p<0.05).
Conclusion
Uric acid concentrations were positively related to the occurrence of metabolic syndrome and its components, and there were differences between genders. Our results indicate serum uric acid as a potential biomarker for patients with cardiometabolic risk.
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