einstein (São Paulo). 24/Apr/2019;17(2):eAO4328.

Applicability of papain solutions in immunohematology

Laís Priscila De , Patrícia Carvalho , Valéria Nogueira Dias Paes , Rosana Rossi , Elenice

DOI: 10.31744/einstein_journal/2019AO4328

ABSTRACT

Objective:

To compare the enzyme activity of different presentations of papain solution to validate in-house preparations.

Methods:

Two papain solutions were prepared, and the third presentation was a commercial solution. Tests were carried out with samples of red cells typed as weak RhD.

Results:

In-house prepared papain solutions showed similar enzyme reactivity, and statistically no differences compared to the enzyme activity of the commercial solution.

Conclusion:

Evaluating the cost-benefit ratio, the in-house prepared papain solutions present more economic advantages, and can be incorporated into immunohematological routines as a way to cope with periods of financial crisis and cost-containment policies.

Applicability of papain solutions in immunohematology
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