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01/Oct/2015
DOI: 10.1590/S1679-45082015AO3321
ABSTRACT Objective To assess the bone health status of children with cerebral palsy and the therapeutic effect of denosumab in a subgroup of children with cerebral palsy and decreased bone mass. Methods Children with cerebral palsy were evaluated according to their motor disability score (classification system gross motor functions III to V), bone density and bone turnover markers. Dual X-ray energy absorption was used to measure the lumbar spine, and total body, except the head. Thereafter a group of children […]
Keywords: Antibodies, monoclonal/therapeutic use; Cerebral palsy/drug therapy; Child; Osteoporosis/drug therapy